Results 81 to 90 of about 5,288 (238)
Abstract Background Differentiating progressive supranuclear palsy (PSP) from other parkinsonian disorders may be challenging. Objectives To investigate the role of transforming growth factor beta‐1 (TGFβ1) in PSP. Methods A total of 33 PSP, 39 Parkinson's disease (PD), 8 multiple system atrophy (MSA) patients, and 50 healthy controls (HC) were ...
Selena Mimmi+16 more
wiley +1 more source
ABSTRACT Neuroimaging with positron emission tomography (PET) has been instrumental in elucidating neurobiological mechanisms behind therapeutical trials in Parkinson's disease (PD). A variety of medical and neurosurgical interventions have been evaluated using many radioligands that reveal molecular basis for target engagement and brain responses in ...
Vijay Dhawan+4 more
wiley +1 more source
Abstract Background Tremor phase‐locked deep brain stimulation (DBS) has been shown to modulate symptom severity in postural tremor, including essential and dystonic tremor, with less energy than existing systems. Previous studies focused on unilateral stimulation; it remains unknown how tremor asymmetry interacts with stimulation in the context of ...
Shenghong He+16 more
wiley +1 more source
Background MR-guided focused ultrasound (MRgFUS) has been developed to treat essential tremor effectively and noninvasively. Currently, clinical examination is used to identify therapeutic efficacy during treatment, but MRgFUS surgery could benefit from ...
Thomas Bancel+16 more
doaj +1 more source
Stroke Mimicking Thalamotomy in Primary Familial Brain Calcification
Movement Disorders Clinical Practice, EarlyView.
Jaakko Kungshamn+4 more
wiley +1 more source
A retraced spiral strategy with semi‐automatic deblurring for volumetric thermometry
Abstract Purpose To develop a 3D MRI‐thermometry technique for transcranial MR‐guided focused ultrasound (MRgFUS). Methods A stack of retraced in‐out (RIO) spirals was incorporated into a 3D, RF‐spoiled, gradient recalled echo (GRE) sequence with a minimized energy deblurring strategy. Bloch simulations examined isochromat precession during RIO readout
Steven P. Allen+4 more
wiley +1 more source
MRI Guided Focused Ultrasound Thalamotomy for Moderate-to-Severe Tremor in Parkinson’s Disease
Background. Thalamotomy is effective in alleviating tremor in Parkinson’s disease (PD). Methods. Seven PD patients, mean age 59.4 ± 9.8 years (range, 46–74) with a mean disease duration of 5.4 ± 2.8 years (range, 2–10) suffering from severe refractory ...
Ilana Schlesinger+6 more
doaj +1 more source
MR thermometry with high precision and temporal resolution by quadratic phase MR fingerprinting
ABSTRACT Purpose To map temperature via the proton resonance frequency‐ (PRF‐) shift with a high frame rate and high precision using quadratic RF excitation phase‐magnetic resonance fingerprinting (qRF‐MRF). Methods A continuous balanced qRF‐MRF sequence was implemented using a constant low‐flip‐angle excitation with quadratic RF excitation phase ...
Sarah J. Garrow+5 more
wiley +1 more source
Objective To explore the methods and curative effect of stereotactic surgery for treating writer's cramp (WC). Methods and Results Two patients with writer's cramp (tremor type) underwent MRI guided stereotactic ventrointermediate (Vim) thalamotomy on
Chao-shi NIU+4 more
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