Results 101 to 110 of about 311,380 (392)

Genetic Evidence Supporting a Role for Brain Region Volume and Functional Network Alterations in Major Depression

open access: yesAdvanced Science, EarlyView.
Genome‐wide analyses indicate that reduced ventral diencephalon and thalamus volumes, along with decreased functional connectivity within the triple network (DMN/CEN/SN), are uniquely associated with the risk of major depression (MD) onset, compared to other similar severe psychiatric disorders.
Ming‐Min Xu   +7 more
wiley   +1 more source

Brain structure in pediatric Tourette syndrome [PDF]

open access: yes, 2017
Previous studies of brain structure in Tourette syndrome (TS) have produced mixed results, and most had modest sample sizes. In the present multicenter study, we used structural magnetic resonance imaging (MRI) to compare 103 children and adolescents ...
Black, K. J   +5 more
core   +2 more sources

Depth‐Customizable 3D Electrode Array for Recording Functional Connectivity in the Brain

open access: yesAdvanced Electronic Materials, EarlyView.
In this study, a depth‐adjustable, flexible 3D multi‐shank electrode array that produces precise neural recordings at various brain depths is developed. Integrating 2D flexible electrode arrays with a modular supporting board allowed the insertion depth to be easily adjusted without re‐fabrication.
Minseok Kim   +5 more
wiley   +1 more source

Critical role for the mediodorsal thalamus in permitting rapid reward-guided updating in stochastic reward environments

open access: yeseLife, 2016
Adaptive decision-making uses information gained when exploring alternative options to decide whether to update the current choice strategy. Magnocellular mediodorsal thalamus (MDmc) supports adaptive decision-making, but its causal contribution is not ...
Subhojit Chakraborty   +3 more
doaj   +1 more source

Unraveling Multimodal Brain Signatures: Deciphering Transdiagnostic Dimensions of Psychopathology in Adolescents

open access: yesAdvanced Intelligent Systems, EarlyView.
This study, utilizing two large‐cohort datasets, employs interpretable neural networks. It demonstrates that incorporating brain morphology and functional and structural networks enhances predictive accuracy for general psychopathology and its dimensions.
Jing Xia, Nanguang Chen, Anqi Qiu
wiley   +1 more source

A cortico-subcortical loop for motor control via the pontine reticular formation

open access: yesCell Reports
Summary: Movement and locomotion are controlled by large neuronal circuits like the cortex-basal ganglia (BG)-thalamus loop. Besides the inhibitory thalamic output, the BG directly control movement via specialized connections with the brainstem.
Emília Bősz   +5 more
doaj  

Thalamic reticular nucleus induces fast and local modulation of arousal state

open access: yeseLife, 2015
During low arousal states such as drowsiness and sleep, cortical neurons exhibit rhythmic slow wave activity associated with periods of neuronal silence.
Laura D Lewis   +6 more
doaj   +1 more source

Case Report: Unusual Neurological Features of Leigh Syndrome due to m.8993T>G Pathogenic Variant in the MT‐ATP6 Gene

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The MT‐ATP6 gene m.8993T>G pathogenic variant has been associated with Leigh syndrome, especially in patients exhibiting a high degree of heteroplasmy. Although patients may present with a wide phenotypic spectrum, characteristic findings include bilateral, symmetric hyperintensities in the basal ganglia and brainstem on brain MRI ...
Ramya Treitel   +2 more
wiley   +1 more source

Medial thalamic stroke and its impact on familiarity and recollection

open access: yeseLife, 2017
Models of recognition memory have postulated that the mammillo-thalamic tract (MTT)/anterior thalamic nucleus (AN) complex would be critical for recollection while the Mediodorsal nucleus (MD) of the thalamus would support familiarity and indirectly also
Lola Danet   +8 more
doaj   +1 more source

Imaging the Centromedian Thalamic Nucleus Using Quantitative Susceptibility Mapping. [PDF]

open access: yes, 2019
The centromedian (CM) nucleus is an intralaminar thalamic nucleus that is considered as a potentially effective target of deep brain stimulation (DBS) and ablative surgeries for the treatment of multiple neurological and psychiatric disorders.
Gutierrez, Lorenzo   +9 more
core  

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