Results 111 to 120 of about 268,852 (297)

Resting state functional thalamic connectivity abnormalities in patients with post-stroke sleep apnoea: a pilot case-control study [PDF]

open access: yes, 2017
OBJECTIVE: Sleep apnoea is common after stroke, and has adverse effects on the clinical outcome of affected cases. Its pathophysiological mechanisms are only partially known.
CALISTRI, VALENTINA   +9 more
core  

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

open access: yesAdvanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing   +10 more
wiley   +1 more source

Presurgical thalamic hubness predicts surgical outcome in temporal lobe epilepsy. [PDF]

open access: yes, 2017
OBJECTIVE: To characterize the presurgical brain functional architecture presented in patients with temporal lobe epilepsy (TLE) using graph theoretical measures of resting-state fMRI data and to test its association with surgical outcome. METHODS: Fifty-
Doucet, Gaelle E.   +5 more
core   +1 more source

In Vivo Electrochemical Monitoring of Safinamide Pharmacokinetics in the Brain Explores Its Correlation With Vision‐Related Neuronal Activity

open access: yesAdvanced Science, EarlyView.
An electrochemical platform based on differential pulse amperometry enables real‐time, selective tracking of safinamide pharmacokinetics in the living brain with high spatiotemporal resolution. When integrated with electrophysiology, this approach reveals that drug‐induced suppression of vision‐related neuronal activity provides mechanistic insight ...
Xiaoke Nan   +9 more
wiley   +1 more source

Target Selection by Frontal Cortex During Coordinated Saccadic and Smooth Pursuit Eye Movement [PDF]

open access: yes, 2007
Oculomotor tracking of moving objects is an important component of visually based cognition and planning. Such tracking is achieved by a combination of saccades and smooth pursuit eye movements.
Bullock, Daniel   +2 more
core   +1 more source

Reduced structural connectivity between left auditory thalamus and the motion-sensitive planum temporale in developmental dyslexia

open access: yes, 2018
Developmental dyslexia is characterized by the inability to acquire typical reading and writing skills. Dyslexia has been frequently linked to cerebral cortex alterations; however recent evidence also points towards sensory thalamus dysfunctions ...
Blank, Helen   +4 more
core   +1 more source

Functional Segregation of Epileptogenicity within the Human Amygdala

open access: yesAnnals of Neurology, EarlyView.
Objective In temporal lobe epilepsy (TLE), the amygdala in the epileptogenic network is underestimated compared to other regions such as the hippocampus. Recent advances in anatomical neuroimaging and stereoelectroencephalography (SEEG) signal analyses could help better understand the involvement of the different amygdala nuclei in the genesis of ...
Odile Feys   +14 more
wiley   +1 more source

Diffusion MRI and α‐Synuclein Seed Amplification Status in Parkinson's Disease

open access: yesAnnals of Neurology, EarlyView.
Objective Positive α‐synuclein seed amplification assay (SAA) is a biomarker found in most people with Parkinson's disease (PD). We explored if free‐water (FW) imaging detects microstructural differences in the brains of patients with early PD with SAA+ or SAA– status.
Shannon Y. Chiu   +145 more
wiley   +1 more source

Altered brain connectivity in sudden unexpected death in epilepsy (SUDEP) revealed using resting-state fMRI. [PDF]

open access: yes, 2019
The circumstances surrounding SUDEP suggest autonomic or respiratory collapse, implying central failure of regulation or recovery. Characterisation of the communication among brain areas mediating such processes may shed light on mechanisms and ...
B, Diehl   +10 more
core  

An elastic segment of the whisker shaft enables coding of the whisking phase via whisker torsion in rats and mice

open access: yesThe Anatomical Record, EarlyView.
An elastic segment was found in the basal part of the whisker shaft in rats and mice. Application of force to the whisker bulb of isolated follicles caused bending and twisting of this segment. Active whisker movements deform this segment, causing whisker shaft deflection and selective activation of mechanoreceptors at different phases of whisking ...
Sebastian Haidarliu   +4 more
wiley   +1 more source

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