Results 71 to 80 of about 268,852 (297)

Location‐Specific Hematoma Volume Predicts Early Neurological Deterioration in Supratentorial ICH

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early neurological deterioration (END) adversely affects outcomes in patients with intracerebral hemorrhage (ICH). This study aimed to determine the location‐specific hematoma volumes for END in supratentorial ICH patients. Methods We retrospectively analyzed supratentorial ICH patients presenting from two prospective cohorts.
Zuoqiao Li, Guilin Meng, Zijie Wang, Xiao Hu, Jing Cheng, Chu Chen, Tiannan Yang, Jiaxin Luo, Zizhen Meng, Xueyun Liu, Qi Li   +10 more
wiley   +1 more source

Medial thalamic stroke and its impact on familiarity and recollection

eLife, 2017
Models of recognition memory have postulated that the mammillo-thalamic tract (MTT)/anterior thalamic nucleus (AN) complex would be critical for recollection while the Mediodorsal nucleus (MD) of the thalamus would support familiarity and indirectly also
Lola Danet, Jérémie Pariente, Pierre Eustache, Nicolas Raposo, Igor Sibon, Jean-François Albucher, Fabrice Bonneville, Patrice Péran, Emmanuel J Barbeau   +8 more
doaj   +1 more source

Effects of the glial modulator palmitoylethanolamide on chronic pain intensity and brain function. [PDF]

, 2019
Background: Chronic neuropathic pain (NP) is a complex disease that results from damage or presumed damage to the somatosensory nervous system. Current treatment regimens are often ineffective.
Alshelh, Zeynab, Di Pietro, Flavia, Henderson, Luke A, Kosanovic, Danny, Macey, Paul M, Mills, Emily P, Vickers, E Russell   +6 more
core   +1 more source

Vestibular Interactions in the Thalamus [PDF]

Frontiers in Neural Circuits, 2015
It has long been known that the vast majority of all information en route to the cerebral cortex must first pass through the thalamus. The long held view that the thalamus serves as a simple hi fidelity relay station for sensory information to the cortex, however, has over recent years been dispelled.
Wijesinghe, Rajiv, Protti, Dario A., Camp, Aaron J.   +2 more
openaire   +3 more sources

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Electrophysiology‐aided DBS targeting the ventral intermediate nucleus in an essential tremor patient with MRI‐incompatible lead: A case report

Physiological Reports, 2023
Essential tremor (ET) is a common disease in the elderly population. Severe, medication‐refractory ET may require surgical intervention via ablation or deep brain stimulation (DBS).
Stefanie Glowinsky, Hagai Bergman, Omer Zarchi, Shlomo Fireman, Johnathan Reiner, Idit Tamir   +5 more
doaj   +1 more source

Vascular changes in the rat brain during chronic hypoxia in the presence and absence of hypercapnia. [PDF]

, 2005
Changes in brain vascularity in adult rats during adaptation to chronic normobaric hypoxia with or without elevated CO(2) were morphometrically investigated.
Hayashida, Yoshiaki, Hirakawa, Haruhisa, Itano, Toshifumi, Kusakabe, Tatsumi, Miyamoto, Osamu, Sumitani, kazunori, Takahashi, Masaru   +6 more
core   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Meditation Experiences, Self, and Boundaries of Consciousness [PDF]

, 2016
Our experiences with the external world are possible mainly through vision, hearing, taste, touch, and smell providing us a sense of reality.
Barnes, Vernon A., Cearley, Shannon M., Jensen, Mike, Ravinder, Jerath   +3 more
core   +1 more source