Results 81 to 90 of about 311,380 (392)

Decreased Left Putamen and Thalamus Volume Correlates with Delusions in First-Episode Schizophrenia Patients

open access: yesFrontiers in Psychiatry, 2017
BackgroundDelusional thinking is one of the hallmark symptoms of schizophrenia. However, the underlying neural substrate for delusions in schizophrenia remains unknown.
Xiaojun Huang   +10 more
doaj   +1 more source

Grey matter atrophy in patients with benign multiple sclerosis

open access: yesBrain and Behavior, 2022
Background Brain atrophy appears during the progression of multiple sclerosis (MS) and is associated with the disability caused by the disease. Methods We investigated global and regional grey matter (GM) and white matter (WM) volumes, WM lesion load ...
Marja Niiranen   +8 more
doaj   +1 more source

Early changes in alpha band power and DMN BOLD activity in Alzheimer's disease: a simultaneous resting state EEG-fMRI study [PDF]

open access: yes, 2017
Simultaneous resting state functional magnetic resonance imaging (rsfMRI)-resting state electroencephalography (rsEEG) studies in healthy adults showed robust positive associations of signal power in the alpha band with BOLD signal in the thalamus, and ...
Babiloni, Claudio   +5 more
core   +1 more source

Mechanical Forces Guide Axon Growth through the Nigrostriatal Pathway in an Organotypic Model

open access: yesAdvanced Science, EarlyView.
Nano‐pulling is a magnetic nanoparticle‐based technology for guiding and promoting the axon growth of induced pluripotent stem cell‐derived dopaminergic neurospheres in vitro or neural progenitors transplanted in the brain tissue. Fine control of axon guidance is essential for reconstructing neural networks and restoring functional connectivity in the ...
Sara De Vincentiis   +7 more
wiley   +1 more source

An Evolutionarily Conserved Network Mediates Development of the zona limitans intrathalamica, a Sonic Hedgehog-Secreting Caudal Forebrain Signaling Center

open access: yesJournal of Developmental Biology, 2016
Recent studies revealed new insights into the development of a unique caudal forebrain-signaling center: the zona limitans intrathalamica (zli). The zli is the last brain signaling center to form and the first forebrain compartment to be established.
Elena Sena   +2 more
doaj   +1 more source

Paraventricular Thalamus Balances Danger and Reward

open access: yesJournal of Neuroscience, 2017
Foraging animals balance the need to seek food and energy against the accompanying dangers of injury and predation. To do so, they rely on learning systems encoding reward and danger. Whereas much is known about these separate learning systems, little is
E. A. Choi, G. McNally
semanticscholar   +1 more source

Conditional expression in corticothalamic efferents reveals a developmental role for nicotinic acetylcholine receptors in modulation of passive avoidance behavior [PDF]

open access: yes, 2003
Prenatal nicotine exposure has been linked to attention deficit hyperactivity disorder and cognitive impairment, but the sites of action for these effects of nicotine are still under investigation. High-affinity nicotinic acetylcholine receptors (nAChRs)
Caldarone, Barbara J   +7 more
core   +2 more sources

Inhibition of Phosphodiesterase 10A by MP‐10 Rescues Behavioral Deficits and Normalizes Microglial Morphology and Synaptic Pruning in A Mouse Model of FOXP1 Syndrome

open access: yesAdvanced Science, EarlyView.
We demonstrate that Foxp1± mice, modeling FOXP1 haploinsufficiency, exhibit behavioral deficits, striatal neuroinflammatory changes including altered microglial complexity and synaptic pruning, and markedly reduced Pde10a expression. Pde10a inhibition starting immediately after birth restores Foxp1± behavior, microglial morphology, and pruning ...
Henning Fröhlich   +8 more
wiley   +1 more source

How to run a brain bank. A report from the Austro-German brain bank [PDF]

open access: yes, 1993
The sophisticated analysis of and growing information on the human brain requires that acquisition, dissection, storage and distribution of rare material are managed in a professional way.
Gsell, W.   +9 more
core  

Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine

open access: yesAdvanced Science, EarlyView.
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang   +4 more
wiley   +1 more source

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