Results 101 to 110 of about 22,512 (233)

Br J Haematol [PDF]

open access: yes
Thalassaemia is caused by genetic globin defects leading to anaemia, transfusion-dependence and comorbidities. Reduced survival and systemic organ disease affect transfusion-dependent thalassaemia major and thalassaemia intermedia. Recent improvements in

core  

Thalassaemia

open access: yes, 2022
Thalassaemia is a diverse group of genetic disorders with a worldwide distribution affecting globin chain synthesis. The pathogenesis of thalassaemia lies in the unbalanced globin chain production, leading to ineffective erythropoiesis, increased ...
Kwiatkowski, J.L.   +2 more
core  

Impact of Heat Block Drying on Morphologic Preservation and Staining of Peripheral Blood Smears

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Morphologic evaluation of the peripheral blood smear is critical for diagnosis and ruling out certain hematologic disorders. While air‐drying is standard, some laboratories may use heat blocks to expedite drying. Excessive heat may induce morphologic artifacts, but there is a lack of systematic literature on this practice ...
Ryan C. Shean   +4 more
wiley   +1 more source

Thalassaemia

open access: yes, 1998
Thalassaemia is a diverse group of genetic disorders with a worldwide distribution affecting globin chain synthesis. The pathogenesis of thalassaemia lies in the unbalanced globin chain production, leading to ineffective erythropoiesis, increased ...
Aydinok, Yesim   +3 more
core   +1 more source

Differentiating β‐Thalassaemia From Iron Deficiency: Performance and Cut‐Off Dependency of More Than 40 Red Cell Discrimination Indices in a Large German Cohort

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background Since the 1970s, more than 40 red blood cell–based formulas have been proposed to differentiate β‐thalassaemia trait (BTT) from iron deficiency (ID) and iron deficiency anaemia (IDA), the main causes of microcytic anaemia. In Germany, where haemoglobinopathies are rare in the autochthonous population but increasingly encountered due
Rafid Al‐Nabhan   +2 more
wiley   +1 more source

A retrospective analysis of the antigen‐negative red blood cell supply conducted at a single centre in China

open access: yesTransfusion Medicine, EarlyView.
Abstract Objective This study aimed to analyse the distribution and demand patterns of antigen‐negative red blood cells (RBCs) in Shandong Province, China (2022–2024), with a focus on ABO blood groups and clinically significant antigens. The research was designed to provide rigorous data for advancing precision transfusion protocols and to establish a ...
Aiping Zhao   +7 more
wiley   +1 more source

Prevalence of thalassaemia among childbearing-age Li and Han populations in Hainan Province

open access: yesHematology
Objectives Accurate epidemiological data are crucial for effective disease prevention and treatment. We conducted a large-scale survey to explore the thalassaemia prevalence and spectrum among the two major ethnic groups in Hainan Province.Methods A ...
Fangchao Tao   +8 more
doaj   +1 more source

Study of Pregnancy Outcome in E-Beta Thalassaemia Mothers [PDF]

open access: yes, 2009
Forty eight E-Beta thalassaemia patients were studied in NRS Medical College, Kolkata, West Bengal during the period from 2000-2006. In all patients Hb% ranged from 5.2g% - 9.6g%.
Maitryaee Bhattacharyaya   +3 more
core  

A global survey of blood transfusion practices for patients with sickle cell disease

open access: yesTransfusion, EarlyView.
Abstract Background Sickle cell disease (SCD) affects over 7 million people globally, with blood transfusion remaining a cornerstone of management. However, contemporary transfusion practices across diverse settings remain poorly characterized. We evaluated global transfusion practices for patients with SCD to identify gaps and inform resource ...
Jeremy W. Jacobs   +18 more
wiley   +1 more source

Racial disparities in anaemia associated with paediatric chronic kidney disease

open access: yes
British Journal of Haematology, EarlyView.
Manya Raina   +3 more
wiley   +1 more source

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