Results 111 to 120 of about 22,512 (233)

Improvement of Sickle Cell Disease Care Mitigates the Healthcare Utilization Induced by Increased Prevalence: Experience of a Tertiary Pediatric Center

Pediatric Blood &Cancer, Volume 73, Issue 10, October 2026.
ABSTRACT Background Sickle cell disease (SCD) has undergone major changes in the last decades. Its prevalence has been steadily increasing and numerous advances have been made in the management of the disease. However, the effect in real‐life setting of these major changes is unknown, particularly in a Canadian environment. Procedure We aimed to assess
Maude Cigna, Alexia Muresan, Estelle Lecluze, Karine Leduc, Nathalie Fournier, Maria Tamer, Jean‐François Delisle, Jeremi Charbonneau, Annie Viau, Jessica Darilus, Marie‐Joëlle Doré‐Bergeron, Valérie Arsenault, Evelyne Doyon‐Trottier, Stéphanie Forte, Nancy Robitaille, Yves Pastore, Thomas Pincez   +16 more
wiley   +1 more source

Expression of CD55, CD59, and CD35 on red blood cells of β-thalassaemia patients

, 2017
Aim of the study : β-thalassaemia (β-Thal) is considered a severe, progressive haemolytic anaemia, which needs regular blood transfusions for life expectancy.
Mustafa Yildiz, Erdal Kurtoğlu, Ayşegül Uğur Kurtoğllu, Belkls Koçtekin, Selen Bozkurt   +4 more
core   +1 more source

Diagnosis of Beta-Thalassaemia Carriers in the Sultanate of Oman

Sultan Qaboos University Medical Journal, 2006
Background: Haemoglobinopathies are a major cause of morbidity in the Sultanate of Oman and premarital screening is being encouraged in order to reduce the number of affected births.
Shahina Daar, David Gravell
doaj  

Alpha-thalassaemia

, 2008
Alpha-thalassaemia is one of the most common human genetic disorders. Couples in which both partners carry alpha 0-thalassaemia traits have a 25% risk of having a fetus affected by homozygous alpha-thalassaemia or haemoglobin Bart's disease, with severe ...
Leung, WC, Leung, KY, Chan, V, V. Chan, Tang, MHY, Lau, ET, K.Y. Leung, E.T. Lau, W.C. Leung, M.H.Y. Tang   +9 more
core   +1 more source

The Role of Ferroptosis Induced by Iron Overload in Osteoblast and Osteoclast Function

Cell Biology International, Volume 50, Issue 10, October 2026.
ABSTRACT Iron overload disrupts bone homeostasis by suppressing osteoblast survival and mineralization, while promoting osteoclastogenesis. As a programmed cell death driven by iron‐dependent lipid peroxidation and glutathione peroxidase 4 (GPX4) downregulation. This study investigated the role of ferroptosis in bone cells under iron overload. Exposure
Supagarn Sooksawanwit, Kornkamon Lertsuwan, Natnicha Tannop, Ploypapus Lapatkeattisukul, Thanayuth Jenpichitkulchai, Nittiyaporn Sotapong, Jarinthorn Teerapornpuntakit, Tueanjai Khunluck, Siriwan Punvilai, Narattaphol Charoenphandhu   +9 more
wiley   +1 more source

Guidelines for the Clinical Management of Thalassaemia [Internet]

, 2014
Written by some of the world’s leading authorities on haemoglobin disorders, this second revised edition of Guidelines for the Clinical Management of Thalassaemia provides medical professionals with a clear, comprehensive guide to the optimal treatment ...
MD. Cappellini, J. Porter, A. Eleftheriou, A. Taher, A. Cohen, A. Piga   +5 more
core   +2 more sources

Multisystem Complications in Non‐Transfusion‐Dependent β‐Thalassemia Intermedia: A Case Highlighting the Need for Early Intervention

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT This case highlights that severe complications of non‐transfusion‐dependent β‐thalassemia may be preventable with appropriate monitoring and timely intervention; however, once established, multisystem complications can be challenging to treat.
Oldooz Aloosh, Seyedeh Esmat Hosseini, Mohammad Karimi   +2 more
wiley   +1 more source

Successful Management of Severe Hepatic Acute Graft‐Versus‐Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation in a Child With β‐Thalassemia Major: Clinical Lessons From Early Therapeutic Escalation

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Severe hepatic acute graft‐versus‐host disease can occur early after allogeneic hematopoietic stem cell transplantation without skin involvement, presenting with rapidly progressive cholestatic liver dysfunction. Early recognition and prompt escalation to multimodal immunosuppressive therapy achieve complete biochemical remission and durable ...
Hind Alhiraki, Amal Ali Fares, Maged Kheder   +2 more
wiley   +1 more source

Prevalence of β-thalassaemia trait among school-going children in Jawadhi Hills: A School-based cross-sectional study

Journal of Family Medicine and Primary Care
Objectives: Nearly 8.9% of the total Indian population is constituted by tribal groups. The burden of haemoglobinopathies, especially β-thalassaemia, is more prominent among these populations than non-tribal populations.
Sam M. David, Eunice Sindhuvi, Midhun Sasikumar, D. Beula, Anuradha Rose, Kuryan George, S. Shanthi, Biju George   +7 more
doaj   +1 more source

Evaluating Reproductive Health Recommendations in CPGs for Sickle Cell Disease: An Umbrella Review

Clinical and Public Health Guidelines, Volume 3, Issue 4, October 2026.
ABSTRACT Background Individuals with sickle cell disease or trait (SCD/T) face significant reproductive health risks, highlighting the need to assess the best available evidence on their reproductive health needs. Objectives To assess the quality of SCD/T clinical practice guidelines and evaluate the key characteristics and quality of their ...
Lisa R. Roberts, Marc Julmisse, Safiye Sahin, Jan M. Nick, Shanalee Tamares   +4 more
wiley   +1 more source