Results 31 to 40 of about 22,512 (233)
Emergency Management of Thalassaemia
, 2021 AUB Faculty Publication.This handbook aims to provide a brief evaluation of the situations in which a thalassaemia patient may seek help beyond the specialized environment he-she is used to.
Porter, John, Mufarrij, Afif, Taher, Ali
core
Health and Quality of Life Outcomes, 2019 Background Thalassaemia is a chronic disease without an effective cure in a majority. The clinical management has improved considerably during recent years; however, minimal attempts are made to up lift the quality of life among patients, especially in ...
Sachith Mettananda +6 more
doaj +1 more source
Co-Incidence or Co-Existence? Acute Lymphoblastic Leukaemia in HbE-alpha Thalassaemia: A Case Report with Review of Literature [PDF]
Journal of Clinical and Diagnostic Research, 2015 Haemoglobin E (HbE) is a Haemoglobin variant that commonly occurs in many places in Asia. As β thalassaemia and α thalassaemia also occur in the same regions, the co-inheritance of these conditions leads to various phenotypic forms.
Rithika Rajendran +3 more
doaj +1 more source
Genes and Diseases, 2021 The incidence of haemoglobinopathy is high in China, especially south of the Yangtze River. However, the exact status of haemoglobinopathy in Sichuan is unknown.
Xia Yu +6 more
doaj +1 more source
, 2012 Although thalassaemia is highly prevalent in the Asia- Pacific region, clinical data on efficacy and safety profiles of deferasirox in patients from this region are rather limited.
邱昌芳;林凱信 +1 more
core +1 more source
Guidelines for the management of nn transfusion dependent thalassaemia (NTDT)
, 2013 Excerpt The term thalassaemia intermedia describes a form of thalassaemia of intermediate severity between the major, transfusion-dependent forms of the disease and the symptomless carrier states.
E. Vichinsky +4 more
core +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
BMC Public Health, 2011 Background Thalassaemia is a common public health problem in Malaysia and about 4.5 to 6% of the Malays and Chinese are carriers of this genetic disorder.
George Elizabeth +2 more
doaj +1 more source
American Journal of Hematology, EarlyView.ABSTRACT Children with SCD have elevated stroke risk, correlated with cerebral blood flow velocity (CBFV). HOPE Kids 2 was a phase 3, multicenter, double‐blind, placebo‐controlled trial evaluating the effect of voxelotor on CBFV. Participants aged 2 to < 15 years with SCD (HbSS/HbSβ0) and conditional CBFV (170 to < 200 cm/s) were randomized 1:1 to ...
Halima Bello‐Manga +58 more
wiley +1 more source