Results 21 to 30 of about 22,512 (233)
Journal of International Medical Research, 2022 Objective To evaluate a novel reverse dot blot assay for the simultaneous detection six types of common α-thalassaemia alleles (three deletional and three common non-deletional mutations) and 19 types of common β-thalassaemia alleles in a Chinese ...
Hong-Feng Liang +8 more
doaj +1 more source
Screening of thalassaemia carriers and its limitations [PDF]
, 2014 The α and β-thalassaemias (thal) are common genetic disorders of globin chain synthesis where the carriers have deficiency of α or β globin chain respectively.
George, Elizabeth
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Optimising Haematopoietic Stem Cell Transplantation: Enhancing Myeloablation Sensitivity and Alleviating Anaemia Using Roxadustat (FG-4592). [PDF]
Cell ProlifThe use of FG‐4592 in the process of myeloablation can promote haematopoietic cell apoptosis for more effective myeloablation, maintain the number of RBC and may create a pluripotent microenvironment suitable for donor cells, so as to enable more effective haematopoietic reconstruction of donor cells in vivo.
Yang G +8 more
europepmc +2 more sources
Genetic and Epigenetic Therapies for β-Thalassaemia by Altering the Expression of α-Globin Gene
Frontiers in Genome Editing, 2021 β-Thalassaemia is caused by over 300 mutations in and around the β-globin gene that lead to impaired synthesis of β-globin. The expression of α-globin continues normally, resulting in an excess of α-globin chains within red blood cells and their ...
Sachith Mettananda, Sachith Mettananda
doaj +1 more source
HbE β-Thalassaemia in Malaysia: revisited [PDF]
, 2013 HbE β – thalassaemia is a public health problem in Malaysia and the most common type of thalassaemia seen in the Malays. It shows considerable diverse phenotypes.
George, Elizabeth
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Ibn Al-Haitham Journal for Pure and Applied Sciences, 2018 β-thalassaemia consists of 3 chief forms: thalassaemia primary (other called "cooley's Anaemia" or "Mediterranean durability Anaemia"), thalassaemia intermedia or thalassaemia minor also frequent termed "β-thalassaemia carrier", "β ...
Mohammed Q. saadoon, Bushra H. Ali
doaj +1 more source
Diagnosis of α-thalassaemia by colorimetric gap loop mediated isothermal amplification
Scientific Reports, 2023 α-Thalassaemia is an inherited haemoglobin disorder that results from the defective synthesis of α-globin protein. Couples whom both carry the α-thalassaemia 1 gene are at risk of having a foetus with the most severe thalassaemia, Hb Bart’s hydrops ...
Worakawee Chumworathayee +4 more
doaj +1 more source
BMJ Open, 2020 Objective Thalassaemia is the most common inherited blood disorder in Malaysia. This study aims to report the current status of thalassaemia in Malaysia and provide a comprehensive understanding of the disease through data obtained from the Malaysian ...
Hishamshah Mohd Ibrahim +16 more
doaj +1 more source
Thalassemia Reports, 2012 Dear Participants,On behalf of the Turkish Federation of Thalassaemia (TFT), we are honoured to invite you to the 12th International Conference on Thalassaemia and the Haemoglobinopathies and the 14th International Conference for Patients and Parents ...
Duran Canatan, Panos Englezos
doaj +1 more source
Guidelines for the Management of Non Transfusion Dependent thalassaemia (NTDT)
, 2021 AUB Faculty Publication.One of the main strategies of the Thalassaemia International Federation (TIF) has been the development of standards and guidelines for the clinical management of patients with thalassaemia. In this effort, TIF published Guidelines
Vichinsky, Elliott P. +2 more
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