Results 171 to 180 of about 219,391 (317)

Chromatin‐associated DEK proteins maintain H3K27me3 balance and coordinate developmental transitions in plants

New Phytologist, EarlyView.
Summary Chromatin organization and histone modifications play essential roles in regulating gene expression during development. DEK is a conserved chromatin‐associated protein implicated in DNA topology and transcriptional regulation, yet its in vivo function in plants has remained elusive.
Miyuki Nakamura, Heinrich Bente, Maria Derkacheva, Matthew Gentry, Katarina Landberg, Mattias Thelander, Eva Sundberg, Lars Hennig, Claudia Köhler   +8 more
wiley   +1 more source

Deletional a-thalassemia 1 gene detection and hematological analysis in carrier with β-thalassemia

Journal of Associated Medical Sciences, 2012
There are high prevalence of β-thalassemia and α-thalassemia in the upper Northern Thailand. Thus, the interaction between β-thalassemia and α-thalassemia can be occurred.
Sitthichai Panyasai
doaj  

Insulin-like growth factor-1 levels in children with Beta-thalassemia minor [PDF]

, 2008
Objective: Growth retardation in children with b-thalassemia major is multifactorial. Some etiologies described for this condition are hemochromatosis, disturbed growth hormone (GH) / insulin growth factor-1 (IGF-1) axis, undernutrition and ...
Hamdollah Karamifar, Mehran Karimi, Nargrs Sobhani   +2 more
core  

Malaria Screening and Treatment in Hematopoietic Cell Transplant Donors and Sickle Cell Disease Candidates/Recipients: A Case Series Using Malaria Polymerase Chain Reaction Testing and a Literature Review

Transplant Infectious Disease, EarlyView.
Malaria polymerase chain reaction (PCR) testing is more sensitive than conventional diagnostics. Routine PCR screening of at‐risk asymptomatic hematopoietic cell donors and transplant candidates may prevent unnecessary deferrals or treatment. In our experience, PCR negativity during screening or after treatment supports donor/candidate eligibility ...
Mary M. Czech, Sanchita Das, Emily Limerick, Courtney Fitzhugh, Matthew Hsieh, Jennifer Cuellar‐Rodriguez   +5 more
wiley   +1 more source

Follow-Up of 3-Year Luspatercept Treatment in a Transfused ß-Thalassemia Patient. Bone Marrow: An Undervalued Iron Store. [PDF]

EJHaem
ABSTRACT Introduction Treatment with luspatercept may improve transfusion requirements in transfusion‐dependent thalassemia (TDT), but the improved erythroid maturation in the bone marrow influences body iron distribution. Case Report We report on sequential organ iron measurements in a TDT patient under luspatercept treatment.
Bleeke M, Niekrens C, Datta S, Grosse R, Longo F, Molwitz I, Fischer R.   +6 more
europepmc   +2 more sources

Dengue with Normal Platelet Count and no Hemoconcentration: Automated Hematogram in Cases with Underlying Thalassemia [PDF]

, 2019
Beuy Joob, Viroj Wiwanitkit
openalex   +1 more source

Position statement from the British Society of Blood and Marrow Transplantation and Cellular Therapy on insertional oncogenesis in gene‐engineered advanced cell therapy products for treatment of haematological disorders

British Journal of Haematology, EarlyView.
S. Ghorashian, R. Sanderson, J. Lee, A. Black, M. A. O'Reilly, D. I. Marks, J. Snowden, D. Richardson, E. Olavarria   +8 more
wiley   +1 more source

Characterisation of RHD and RHCE variations in blood donors from Jazan Province, Southwestern Saudi Arabia

Transfusion Medicine, EarlyView.
Abstract Background and Objectives Rh is among the most important and highly polymorphic blood group systems due to the proximity of the RHD and RHCE genes, which encode numerous highly immunogenic antigens. However, in areas of Saudi Arabia with a high prevalence of hemoglobinopathy, the molecular characteristics of RHD and RHCE variations are lacking.
Maymoon M. Madkhali, Mayisah Khormy, Abdullah A. Meshi, Bandar Kameli, Khaled Ghazwani, Ohoud Sufyani, Salha Hakami, Yahya Khawaji, Abdullah A. Mobarki, Khaled Essawi, Waleed Hakami, Yara Alyahyawi, Aymen M. Madkhali, Gasim Dobie, Hassan A. Hamali   +14 more
wiley   +1 more source

A validation study of the in vitro performance of hypoxic red blood cells for transfusion across centers in Europe

Transfusion, EarlyView.
Abstract Background Refrigerated storage of red cell concentrate (RCC) leads to metabolic, oxidative, and structural changes that impair functionality and viability. These changes can be attenuated by hypoxic storage. Objective This study assessed the quality of leucocytes‐reduced (LR), O2/CO2 reduced red blood cells (RBC) stored for 42 days after pre ...
Vanessa Agostini, Reinhard Henschler, Turid Helen Felli Lunde, Einar Klæboe Kristoffersen, Geir Hetland, Elena Danilova, Agathe Martin, Michel Prudent, Giuliano Grazzini, Lucia De Franceschi, Iwona Walicka, Joseph Wagner, Laurel Omert   +12 more
wiley   +1 more source

Co-inheritance of --MED double gene deletion and αααAnti3.7 triplication on α-globin gene in Mazandaran at 2016

Research in Molecular Medicine, 2017
Alpha Thalassemia is one of the most prevalent disorders worldwide with a [T1] high carrier rate in Mazandaran province (north of Iran). Carriers of --MED double gene deletion are at risk of having a child with hemoglobin  haemoglobin[T2] 
Hossein Jalali, Mehrnoush Kosaryan, Mohammad Reza Mahdavi, Mehrad Mahdavi   +3 more
doaj