Third-degree heart block in thalassemia major: A case report [PDF]
, 2012 Background: First and second-degree heart blocks are partly common rhythm disorders in thalassemic patients but complete heart block is a very rare complication of iron overload cardiomyopathy.
Hosseini, S.M., Maleki, A.R., Nikyar, B.
core +1 more source
Appraisal of patient-reported outcome measures in analogous diseases and recommendations for use in phase II and III clinical trials of pyruvate kinase deficiency [PDF]
, 2018 Purpose: Pyruvate kinase deficiency (PKD) is a rare disease and understanding of its epidemiology and associated burden remains limited. With no current curative therapy, clinical manifestations can be life threatening, clinically managed by maintaining ...
Ionova, Tatyana +3 more
core +2 more sources
Hypogonadism in thalassemia major patients
Journal of Clinical & Translational Endocrinology, 2016 Despite recent advances in iron chelation therapy, excess iron deposition in pituitary gonadotropic cells remains one of the major problems in thalassemic patients. Hypogonadism, mostly hypogonadotropic hypogonadism, is usually detected during puberty.
Sasima Srisukh +2 more
openaire +3 more sources
Vox Sanguinis, EarlyView.Abstract Background and Objectives The presence of warm autoantibodies (WAAs) complicates pre‐transfusion and compatibility testing. Despite attempts to provide antigen‐matched red blood cells (RBCs), the risk of alloimmunization remains. Rates of alloimmunization and indications for transfusion were reviewed to streamline testing and RBC provision ...
S. Hutspardol +8 more
wiley +1 more source
Immune Response of Thalassemia Major Patients in Indonesia with and without Splenectomy
Acta Medica Indonesiana, 2016 Aim: to describe non-spesific and specific immune response profile in Indonesian thalassemia major with and without splenectomy. Methods: this study was held at Thalassaemia Centre, Cipto Mangunkusumo Hospital Jakarta on September 2013 – February 2014 ...
Teny T Sari1 +6 more
doaj +2 more sources
Pediatric Blood &Cancer, Volume 73, Issue 2, February 2026.ABSTRACT Background Adverse childhood experiences (ACEs) are stressful or traumatic events prior to age 18 that are known to have a lasting impact on individuals’ health and well‐being. There is a gap in understanding the relationship between ACEs and Other Life Stressors and health status for adults with sickle cell disease (SCD).
Marsha Treadwell +8 more
wiley +1 more source
Effects of vitamin e and zinc supplementation on antioxidants in beta thalassemia major patients [PDF]
, 2011 Objective: In beta thalassemic patients, tissue damage occurs due to oxidative stress and it happens because of the accumulation of iron in the body. This study was conducted to determine the effect of zinc and vitamin E supplementation on antioxidant ...
Aboomardani, M. +5 more
core +1 more source
Serum Neutrophil Gelatinase-Associated Lipocalin as a Biomarker for Early Renal Dysfunction in Adult Egyptian Patients with b-Thalassemia Major [PDF]
, 2018 M.D. AMAL S. EL-BENDARY NELLY D. EL-SHALL +1 more
openalex +1 more source
Comparison of the effectiveness of ACT therapy and cognitive-behavioral therapy on life expectancy and blood hemoglobin in patients with thalassemia major [PDF]
, 2023 Mahmoud Rasoulian +4 more
openalex +1 more source
Mediterranean Journal of Hematology and Infectious Diseases, 2016 Iron overload in patients with thalassemia major (TM) affects glucose regulation and is mediated by several mechanisms. The pathogenesis of glycaemic abnormalities in TM is complex and multifactorial. It has been predominantly attributed to a combination
V. De Sanctis +11 more
semanticscholar +1 more source