Results 41 to 50 of about 694,655 (127)
The Incidence of Minor β-thalassemia Among Individuals Participated in Premarital Screening Program in Ardabil Province: North-west of Iran [PDF]
Introduction: The most effective way to prevent thalassemia is to screen for the disease at the population level and then to evaluate the molecularity of individuals.
مظهری, نهاله +2 more
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Biotechnology and Bioengineering, EarlyView.Lifecycle perspective on cell and gene therapy manufacturing challenges and enabling GMP solutions. ABSTRACT Cell and gene therapies (CGTs) are revolutionizing modern medicine; however, making these advanced medicines scalable and readily available to commercial manufacturers worldwide is a major challenge. The number of approved CGT products continues
Rajath Samaga +2 more
wiley +1 more source
Prevalence of Minor β-thalassemia Based on RBC Indices among Final Suspected Individuals in Premarital Screening Program Referred to Genetic Laboratories [PDF]
International Journal of Hematology-Oncology and Stem Cell Research, 2010 "nAbstract "nIntroduction: The current study evaluated the value of red blood cell (RBC) indices and the corresponding cut- off points for β-thalassemia control programs in Iran.
Alireza Moafi +5 more
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Phenotypic and Genotypic Analysis of Two Rare Cases of ‐‐SEA/‐α4.3 HbH Disease
Journal of Clinical Laboratory Analysis, EarlyView.We report two unrelated adult patients with rare deletional HbH disease (genotype ‐‐SEA/‐α4.3). This novel 4.3 kb deletion covering the HBA1 gene is accompanied by X‐Y‐Z segment recombination, which was identified by CycloneSEQ long‐read nanopore sequencing.
Weijia Yang +7 more
wiley +1 more source
Ocular manifestations in thalassemia minor.
, 1982 The authors report the results of a study on 96 subjects affected with thalassemia minor. The study was made at the Center for the Study of Microcythemia of the OORR in Naples.
Pisapia R. +7 more
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Journal of Clinical Laboratory Analysis, EarlyView.This study revealed a β‐thalassemia‐trait‐dominated genetic spectrum in Northern‐Chinese patients with microcytic hypochromic anemia, with _αSEA/αα, HBB:c.316_197C>T and HBB:c.124_127delTTCT being the most prevalent α‐ and β‐globin genotypes. Using LASSO regression, we constructed a nomogram based on four routine complete‐blood‐count parameters (RBC ...
Wen‐jie Yu +6 more
wiley +1 more source
Difficulties in diagnosing thalassemia minor
, 2021 Here we outline a practical approach to the detection of thalassemias in some clinical settings. Any patient with a low mean corpuscular volume (MCV) with or without anemia or a neonatal screening result indicating possible presence of thalassemia minor ...
Karaman, Serap, Apak, Hilmi
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JPGN Reports, EarlyView.Abstract Plummer–Vinson syndrome (PVS) is characterised by the triad of dysphagia, iron‐deficiency anaemia, and proximal oesophageal webs. While well described in adults, paediatric cases remain exceptionally rare, particularly in sub‐Saharan Africa.
Paul Mike Tayou Mbobda +2 more
wiley +1 more source
Highlights on the Luspatercept Treatment in Thalassemia
, 2023 Luspatercept has been shown to act as a ligand trap, selectively suppressing the deleterious effects of GDF11 that blocks terminal erythroid maturation, restoring normal erythroid differentiation and improving anemia in animal models of &beta ...
Yesim Aydinok, Aydinok, Yesim
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, 2022 From Volume 1 (2011) to Volume 11 (2021), Thalassemia Reports [...
Thalassemia Reports Editorial Office Thalassemia Reports Editorial Office
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