Results 181 to 190 of about 28,078 (291)
Targeted Expansion of Treg Cells to Induce Immune Tolerance after Kidney Transplantation
A dual‐targeting nanoparticle platform that selectively engages graft stromal cells via CD248 receptors while employing kidney‐ specific promoters (NPHS2) to drive localized IL‐ 2/TGF‐βexpression is developed. This approach achieves three therapeutic objectives:1) intragraft Treg polarization without systemic cytokine exposure;2) reduced dependence on ...
Tong Lu +18 more
wiley +1 more source
This study reveals how hematite crystal facets govern heterogeneous (photo)‐Fenton degradation of organic dyes. Facet‐dependent differences in H2O2 decomposition and reactive oxygen species generation are demonstrated, providing mechanistic insights that inform environmental strategies for water purification and pollutant remediation. Abstract Although
Ping Chen +15 more
wiley +1 more source
Determination of thallium by a dithizone mixed-color method [PDF]
Roy S. Clarke, Frank Cuttitta
openalex +1 more source
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun +23 more
wiley +1 more source
Dynamic deep marine oxygenation during the Early and Middle Paleozoic. [PDF]
Ostrander CM +6 more
europepmc +1 more source
B‐EPIC: A Transformer‐Based Language Model for Decoding B Cell Immunodominance Patterns
B‐Epic: Achieving high‐accuracy B cell epitope prediction through Transformer architecture. Comprehensive validation demonstrates B‐Epic's robust performance across diverse datasets. B‐Epic facilitates vaccine development for H. pylori and EBV, addressing critical public health challenges.
Jun‐Ze Liang +16 more
wiley +1 more source
A machine learning framework for predicting cognitive impairment in aging populations using urinary metal and demographic data. [PDF]
Ren F +5 more
europepmc +1 more source
Centimeter‐Scale Self‐Assembling Tendon Organoids Drive Tissue Regeneration
Centimeter‐scale tendon organoids are engineered by mimicking the extracellular matrix and optimizing chemical cues to guide tendon stem/progenitor cells. These large, self‐assembling constructs overcome conventional size limitations and exhibit enhanced tenogenic differentiation, extracellular matrix production, and mechanical resilience. Their tissue‐
Tianshun Fang +16 more
wiley +1 more source

