Results 111 to 120 of about 175,765 (269)

Focus on Arctic change: transdisciplinary research and communication [PDF]

, 2023
Ylva Sjöberg, Frédéric Bouchard, Susanna Gartler, Annett Bartsch, Donatella Zona   +4 more
openalex   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Three bilberry bHLHs of subgroup IIIf play divergent roles in fruit anthocyanin and flavonoid biosynthesis

Scientific Reports
Bilberry (Vaccinium myrtillus L.) fruit are one of the best natural sources of anthocyanins. Anthocyanin and flavonoid biosynthesis are transcriptionally regulated by the conserved MBW complex, including R2R3 MYB, basic helix-loop-helix (bHLH) and WD40 ...
Katja Karppinen, Lauri Raami, Hilary Edema, Muhammad Furqan Ashraf, Heikki M. Salo, Richard V. Espley, Laura Jaakola   +6 more
doaj   +1 more source

Estimating Spatial Changes Over Time of Arctic Sea Ice using Hidden 2×2 Tables

, 2018
Bohai Zhang, Noel Cressie
openalex   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Front Cover

Nordlit: Tidsskrift i litteratur og kultur, 2019
This file will be uploaded by November 11, 2019.
Christian Beyer, Juliane C. Bockwoldt, Emil Lundedal Hammar, Holger Pötzsch   +3 more
doaj  

Diverse influences of spring Arctic Oscillation on the following winter El Niño-Southern Oscillation in CMIP5 models

, 2020
Yuqiong Zheng
openalex   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Bowhead whale faeces link increasing algal toxins in the Arctic to ocean warming [PDF]

Kathi A. Lefebvre, Patrick Charapata, Raphaela Stimmelmayr, Peigen Lin, Robert S. Pickart, Katherine A. Hubbard, Brian D. Bill, Gay Sheffield, Emily K. Bowers, Donald M. Anderson, Evangeline Fachon, Rick Thoman   +11 more
openalex   +1 more source