Results 121 to 130 of about 2,858,223 (342)

Hydrophobicity causes anomalous migration of cystine/glutamate antiporter SLC7A11 in SDS‐PAGE with low acrylamide concentration

open access: yesFEBS Open Bio, EarlyView.
SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel   +13 more
wiley   +1 more source

In situ simulation training strengthened bachelor of nursing students’ experienced learning and development process– a qualitative study

open access: yesBMC Nursing
Background In advanced clinical learning labs on campus, high-fidelity simulation has become an essential educational approach in the Bachelor of Nursing Education programme.
Karina Karlsen   +3 more
doaj   +1 more source

Arctic teleconnection on climate and ozone pollution in the polar jet stream path of eastern US [PDF]

open access: yesarXiv
Arctic sea ice is in reduction and has been a key significant indicator of climate change. In this paper, we explore Arctic Sea ice extent data to identify teleconnection with weather change in the polar and sub-tropical jet stream intersection in eastern United States (US) and hence the potential influence in ground level ozone pollution.
arxiv  

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

open access: yesFEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang   +9 more
wiley   +1 more source

Chronotype and response to training during the polar night: a pilot study

open access: yesInternational Journal of Circumpolar Health, 2017
Background: An individual’s chronotype influences his or her physiological rhythms. Some studies have looked at the effect of time of day on the responses to exercise, but studies on the effect of long-term training are lacking. Objective:  To report the
Jacopo Antonino Vitale   +4 more
doaj   +1 more source

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei   +7 more
wiley   +1 more source

Arctic Sea Ice Image Super-Resolution Based on Multi-Scale Convolution and Dual-Gating Mechanism [PDF]

open access: yesarXiv
Arctic Sea Ice Concentration (SIC) is the ratio of ice-covered area to the total sea area of the Arctic Ocean, which is a key indicator for maritime activities. Nowadays, we often use passive microwave images to display SIC, but it has low spatial resolution, and most of the existing super-resolution methods of Arctic SIC don't take the integration of ...
arxiv  

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