Results 21 to 30 of about 435,383 (264)

Arkady Mikhailovich Karasik, 1930-1987 [PDF]

, 1988
... One of Karasik's major achievements was his many years' study of the Eurasian Basin of the Arctic Ocean. This study enabled him to develop and substantiate the technique of geohistorical analysis, which, due to his efforts, became technologically ...
of North America, The Arctic Institute
core   +1 more source

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source

Investigation of the Uniformity of Gel Shrinkage by Imaging Tracer Particles Using X‐Ray Microtomography

Advanced Engineering Materials, EarlyView., 2023
A novel method for tracking structural changes in gels using widely accessible microcomputed tomography is presented and validated for various hydro‐, alco‐, and aerogels. The core idea of the method is to track positions of micrometer‐sized tracer particles entrapped in the gel and relate them to the density of the gel network.
Anja Hajnal, Mimololorun Lucy Aiyelari, Martin Dirauf, Pavel Gurikov   +3 more
wiley   +1 more source

Oceans governance in the Arctic [PDF]

, 2008
Global warming is bringing rapid change to the Arctic. The melting of sea ice and glaciers is increasing faster than scientists predicted even a year ago.
de La Fayette, Louise Angélique
core   +1 more source

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

FEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner, Juthamas Khamseekaew, M. Gregor Madej, Linda Geiges, Bardha Azemi, Christine Ziegler, Christoph Korbmacher, Alexandr V. Ilyaskin   +7 more
wiley   +1 more source

Hypsometry and Volume of the Arctic Ocean and Its Constituent Seas [PDF]

, 2002
This paper presents an analysis of the Arctic Ocean and its constituent seas for seafloor area distribution versus depth and ocean volume. The bathymetry from the International Bathymetric Chart of the Arctic Ocean (IBCAO) is used together with limits ...
Aagard, Bischof, Brozovic, Dawes, Dyke, Elverhøi, Fairbanks, Grosswald, Guilderson, Head Department of Navigation and Oceanography (HDNO), Jakobsson, Jakobsson, Kleiber, Mangerud, Martin Jakobsson, Menard, Nørgaard-Pedersen, Pusharovsky, Rudels, Smith, Soluri, Svendsen, Wessel   +22 more
core   +2 more sources

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

The Useless Arctic: Exploiting Nature in the Arctic in the 1870s

Nordlit, 2015
<p align="LEFT">What is the discursive genealogy of an ecological approach to the Arctic? Building on distinctions suggested by Francis Spufford and Gísli Pálsson, this article examines a specific juncture in the history of European–Arctic interaction – the reception of the Austro-Hungarian Arctic Expedition in 1874 – and traces the potential for
Spring, Ulrike, Schimanski, Johan Henrik
openaire   +8 more sources

Brucella NyxA and NyxB dimerization enhances effector function during infection

FEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre, Arthur Louche, Francine C. A. Gérard, Laurent Terradot, Suzana P. Salcedo   +4 more
wiley   +1 more source

Arctic air pollution: Challenges and opportunities for the next decade [PDF]

, 2016
The Arctic is a sentinel of global change. This region is influenced by multiple physical and socio-economic drivers and feedbacks, impacting both the natural and human environment.
Arnold, S. R., Baklanov, A., Brock, C. A., Dibb, Jack E., Eckhardt, S., Fidel, M., Flanner, M. G., Gamble, J., Johnson, N., Law, K. S., Lund, M. T., Melamed, M., Petaja, T., Sharma, S., Starkweather, S. M., Stohl, A., Tanimoto, H., Thomas, J. L., Tynkkynen, V. P., von Salzen, K.   +19 more
core   +1 more source