Results 31 to 40 of about 70,721 (269)
This month, the United States takes over the chairmanship of the Arctic Council, a position it last held in 1998. Since then, global interest in the Arctic has increased, and the council has evolved considerably. What has spurred that interest, and what will the council focus on under U.S. leadership?
openaire +2 more sources
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Risk factors for perinatal mortality in Murmansk County, Russia: a registry-based study
Background: Factors contributing to perinatal mortality (PM) in Northwest Russia remain unclear. This study investigated possible associations between selected maternal and fetal characteristics and PM based on data from the population-based Murmansk ...
Anna A. Usynina +5 more
doaj +1 more source
Rising temperatures in the Arctic affect soil microorganisms, herbivores, and peatland vegetation, thus directly and indirectly influencing microbial CH4 production.
Edda M. Rainer +4 more
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Background Physical inactivity and obesity are global public health challenges. Older adults are important to target for prevention and management of disease and chronic conditions.
Trygve S. Deraas +9 more
doaj +1 more source
The concept of an ‘Arctic Pedagogy’ is enticing. Arctic branding sells: for example, UiT is not just the ‘University of Tromsø’ but also the ‘The Arctic University of Norway’. Moreover, research in Scotland as part of the ‘New Northern Pedagogies Project’ is now investigating “how the principles of Arctic Pedagogy can support teacher education ...
Waterman-Evans, Louis +1 more
openaire +3 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Capture Probe, Metabarcoding, or Shotgun Sequencing: Which Best Reflects Local Vegetation?
Metabarcoding is the most widely applied method for studying plant communities using environmental DNA, with shotgun sequencing and capture probes being alternative methods that aim to retrieve multiple markers or genome‐wide information.
Nichola A. Strandberg +11 more
doaj +1 more source

