Results 41 to 50 of about 598,343 (316)

Sedimentary DNA from lake depocenters maximizes detection of catchment vegetation

open access: yesCommunications Earth & Environment
Sedimentary DNA is becoming an invaluable tool for biodiversity assessments across spatial and temporal scales. Accurate interpretation, however, requires a clear understanding of its origin and taphonomy, from transport to preservation processes within ...
Tulug Gulce Ataman   +4 more
doaj   +1 more source

Complex lifestyle intervention among inactive older adults with elevated cardiovascular disease risk and obesity: a mixed-method, single-arm feasibility study for RESTART—a randomized controlled trial

open access: yesPilot and Feasibility Studies, 2021
Background Physical inactivity and obesity are global public health challenges. Older adults are important to target for prevention and management of disease and chronic conditions.
Trygve S. Deraas   +9 more
doaj   +1 more source

Social Indicators for Arctic Mining [PDF]

open access: yes, 2011
This paper reviews and assesses the state of the data to describe and monitor mining trends in the pan-Arctic. It constructs a mining index and discusses its value as a social impact indicator and discusses drivers of change in Arctic mining.
Crow, Andrew   +4 more
core  

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Risk factors for perinatal mortality in Murmansk County, Russia: a registry-based study

open access: yesGlobal Health Action, 2017
Background: Factors contributing to perinatal mortality (PM) in Northwest Russia remain unclear. This study investigated possible associations between selected maternal and fetal characteristics and PM based on data from the population-based Murmansk ...
Anna A. Usynina   +5 more
doaj   +1 more source

Flux of nutrients from Russian rivers to the Arctic Ocean: Can we establish a baseline against which to judge future changes? [PDF]

open access: yes, 2000
Climate models predict significant warming in the Arctic in the 21st century, which will impact the functioning of terrestrial and aquatic ecosystems as well as alter land‐ocean interactions in the Arctic.
Gordeev, V. V.   +6 more
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

The impact of changes in leisure time physical activity on changes in cardiovascular risk factors: results from The Finnmark 3 Study and SAMINOR 1, 1987–2003

open access: yesInternational Journal of Circumpolar Health, 2018
Objective: The aim of this study was to examine the associations between changes in leisure time physical activity and changes in cardiovascular risk factors over 16 years and whether they differ between two ethnic groups in Norway.
Rune Hermansen   +5 more
doaj   +1 more source

Microsatellite loci among Alaskan rabies hosts: Arctic and red fox [PDF]

open access: yes, 2012
Little is known about the population dynamics between Arctic and red foxes in Alaska and consequences for rabies ecology. Both species carry different variants of rabies and inhabit different environments.
Renshaw, Ben
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

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