Results 61 to 70 of about 938,194 (315)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Formation of Supermassive Black Holes

, 2010
Evidence shows that massive black holes reside in most local galaxies. Studies have also established a number of relations between the MBH mass and properties of the host galaxy such as bulge mass and velocity dispersion.
A Freise, A Heger, A Loeb, A Marconi, A Marconi, A Merloni, A Merloni, A Sesana, A Soltan, AJ Barth, AJ Barth, AM Ghez, AV Gruzinov, B Devecchi, BJ Carr, BJ Carr, C Alcock, C Lacey, CF McKee, CJ Willott, CJ Willott, CL Fryer, D Merritt, D Reed, D Spolyar, DJ Eisenstein, DN Page, E Berti, E Gallo, E Quataert, E Ripamonti, E Ripamonti, EH Wehner, F Hoyle, F Iocco, F Santoro, FC Bosch van den, G Ghisellini, G Lodato, HJ Mo, I Shlosman, J Diemand, J Kormendy, J Magorrian, JA Regan, JC Tan, JC Vernaleo, JE Greene, JF Navarro, JH Wise, JL Johnson, JR Bond, JS Bullock, K Freese, K Gebhardt, K Gebhardt, K Gültekin, K Omukai, K Omukai, KG Arun, L Ferrarese, L Ferrarese, L Ferrarese, L Gao, L Spitzer, LC Ho, M Ajello, M Dijkstra, M Elvis, M Freitag, M Freitag, M Mateo, M Milosavljević, M Ricotti, M Saijo, M Shibata, M Spaans, M Tegmark, M Trenti, M Valluri, M Volonteri, M Volonteri, M Volonteri, M Volonteri, M Volonteri, M Walter, MA Abramowicz, MA Abramowicz, MA Gürkan, MA Gürkan, Marta Volonteri, MC Aller, MC Begelman, MC Begelman, MC Begelman, MC Begelman, MC Begelman, MC Begelman, MC Miller, MG Haehnelt, MG Walker, MG Walker, MJ Turk, MS Bovill, MY Khlopov, N Häring, N Yoshida, NY Gnedin, P Côté, P Madau, PC Clark, PF Hopkins, Q Yu, R Decarli, R Salvaterra, R Schneider, R Schödel, RD Blandford, RD Blandford, RK Sheth, RP Kudritzki, S Hawking, S Tremaine, SA Hughes, SDM White, SE Woosley, SF Portegies Zwart, SF Portegies Zwart, SF Portegies Zwart, SL Shapiro, SM Koushiappas, SP Oh, SR Majewski, T Abel, T Ebisuzaki, T Tanaka, TH Greif, TW Baumgarte, V Bromm, V Bromm, V Bromm, V Springel, VR Eke, W Zhang, X Fan, X Fan, X Fan, YB Zeldovich, YB Zel’Dovich, Z Barkat, Z Haiman   +150 more
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

The “Vendee” of the Russian Revolution of 1905-1907? The Western Provinces and the Black Hundreds

Izvestiya of Altai State University, 2021
The western French department of the Vendee has acquired a certain regional identity in the politics of historical memory not only of the French Revolution but also of the Russian Revolution of 1917-1922. The royalist rebellion of the Vendee peasants between 1793-1796 has become a synonym for a region of mass lower-class counter-revolution.
openaire   +2 more sources

The Ukrainian “Black Hundred”? K.K. Fedevich’s concept as an attempt to “Ukrainize” the Union of the Russian People [PDF]

Rusin, 2021
Historian K.K. Fedevich, author of the book For Faith, Tsar and Kobzar. The Little Russian Monarchists and Ukrainian National Movement (1905–1917) put forward a revisionist concept whereby the Little Russian monarchists and the black-hundredists (primarily, the Pochaev Division of the Union of the Russian People) were the right wing of the Ukrainian ...
openaire   +1 more source

Black Hole Chromosphere at the LHC

, 2002
If the scale of quantum gravity is near a TeV, black holes will be copiously produced at the LHC. In this work we study the main properties of the light descendants of these black holes.
A. Chamblin, A. Ringwald, A.F. Heckler, A.F. Heckler, B. Abbott, C.T. Hill, D.M. Eardley, D.N. Page, G. Landsberg, G.F. Giudice, Haim Goldberg, I. Antoniadis, J. Preskill, J.B. Hartle, J.H. MacGibbon, J.L. Feng, J.M. Cline, K. Hagiwara, K.m. Cheung, L. Anchordoqui, L. Randall, L.A. Anchordoqui, L.A. Anchordoqui, L.A. Anchordoqui, Luis Anchordoqui, M.B. Voloshin, M.B. Voloshin, N. Arkani-Hamed, P. Kanti, P.C. Argyres, R. Emparan, R.C. Myers, R.G. Daghigh, S. Dimopoulos, S. Dimopoulos, S.B. Giddings, S.B. Giddings, S.N. Solodukhin, S.W. Hawking, S.W. Hawking, T. Han, T.G. Rizzo, V. Frolov, V. Frolov   +43 more
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Quantifying Impacts of Aerosol Mixing State on Nucleation-Scavenging of Black Carbon Aerosol Particles

Atmosphere, 2018
Recent observational studies suggest that nucleation-scavenging is the principal path to removing black carbon-containing aerosol from the atmosphere, thus affecting black carbon’s lifetime and radiative forcing.
Joseph Ching, Matthew West, Nicole Riemer   +2 more
doaj   +1 more source

The Radio Scream from black holes at Cosmic Dawn: a semi-analytic model for the impact of radio-loud black holes on the 21 cm global signal [PDF]

Monthly notices of the Royal Astronomical Society, 2019
We use a semi-analytic model to explore the potential impact of a brief and violent period of radio-loud accretion on to black holes (The Radio Scream) during the Cosmic Dawn on the H i hyperfine 21 cm signal.
Aaron Ewall-Wice, Aaron Ewall-Wice, Tzu-Ching Chang, T. Lazio   +3 more
semanticscholar   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source