Results 21 to 30 of about 1,066 (237)

Alexander Pasqualini (1493-1559) architect en vestingbouwkundige

open access: yesBulletin KNOB, 1991
The Italian Alexander Pasqualini, as artillery master in the service of the Lords of Egmond from about 1531 and as an architect in the service of the Duke of Gulik, Kleef and Berg, introduced early Renaissance architecture in the Low Countries ...
Theo van Mierlo
doaj   +1 more source

Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma–Brain Organoid Interfaces

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang   +17 more
wiley   +1 more source

Conversations across time and space: classical traditions in the Andes

open access: yesAnuario Colombiano de Historia Social y de la Cultura, 2001
Ona June night in 1557,Gonzalo Femández de Oviedo, courtier, soldier, imperial official, man of letters and historian, lay on his deathbed, clasping in his hands the key to the fortress of Santo Domingo of which he had been commandant, alcaide, duringthe
Sabine MacCormack
doaj   +2 more sources

NIKHAKHI FORTRESS

open access: yes, 2022
Nikhakhi fortress is situated in Yusufel district of Artvin province (the Republic of Turkey) in 40 km from town Yusufeli, on the road that goes in direction of Speri. The contemporary Turkish name of the village is Yokuşlu while the old name is Nikhakh (
ბოშიშვილი, ალექსანდრე
core  

Stage‐Specific H3K14 and H3K23 Succinylation Orchestrates Insect Metamorphosis and Oogenesis

open access: yesAdvanced Science, EarlyView.
Stage‐specific succinylation of histone H3 at lysine 14 and 23 differentially controls insect metamorphosis and oogenesis through distinct GPCR‐PKC signaling cascades, revealing an evolutionarily conserved epigenetic mechanism that coordinates key life‐history traits.
Yu‐Pu Jing   +9 more
wiley   +1 more source

Microplastics‐Induced Gut Microbiota Dysbiosis Accelerates Alzheimer's‐Like Pathology and Cognitive Decline via the Gut–Brain Axis

open access: yesAdvanced Science, EarlyView.
Microplastics (MPs) breach the gut‐brain axis by triggering taurine‐depleting microbiota dysbiosis that accelerates Alzheimer‐like pathology in 5XFAD mice. Taurine supplementation normalizes autophagy, microglial quiescence, and cognition, and plasma taurine inversely tracks cognitive decline in ADNI participants, revealing a readily translatable ...
Zifeng Wu   +8 more
wiley   +1 more source

Multiscale digital documentation methodology using photogrammetry and GIS: the case of the Real Felipe Fortress of Callao

open access: yesRevista de Expresión Gráfica en la Edificación
As part of a doctoral research project on military architecture in the Viceroyalty of Peru, a study of various historical fortifications was conducted. To analyze their layout, understand the technical principles applied in their design and construction,
Diego Javier Celis-Estrada   +1 more
doaj   +1 more source

Tandem Duplication‐Driven Neofunctionalization of UDP‐Glycosyltransferases Shapes the Diversification of Triterpenoid Saponins in the Cucurbitaceae

open access: yesAdvanced Science, EarlyView.
We present a chromosome‐level genome assembly of Siraitia grosvenorii and, through comparative genomics, uncover a conserved UGT73 tandem array driving triterpenoid saponin diversification in Cucurbitaceae. Crystalized SgUGT73AM30 further reveals the regioselectivity mechanism underlying its catalytic activity.
Guangyi Wang   +13 more
wiley   +1 more source

Oxygen Vacancy‐Mediated Bi─O Unsaturation Coordination in BiOCl for Efficient Photocatalytic Water Purification

open access: yesAdvanced Science, EarlyView.
The incorporation of oxygen vacancies (OVs) presents a viable strategy for fine‐tuning the photocatalytic prowess of BiOCl. A reliable hydrogen annealing reduction technique is employed to precisely design OVs, thereby optimizing the light absorption capacity, as well as the efficiency of carrier migration and separation in BiOCl.
Shuaihao Ma   +11 more
wiley   +1 more source

Forecasting technology costs via the Learning Curve - Myth or Magic?

open access: yes, 2006
To further our understanding of the effectiveness of learning or experience curves to forecast technology costs, a statistical analysis using historical data has been carried out.
Alberth, S.
core   +1 more source

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