Results 41 to 50 of about 840,241 (310)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Constitution and By-Laws, Circle of Friends, Dallas, Texas
, 1965 Constitution and by-laws of the Circle of Friends, a group organized "to establish and promote communication, understanding and harmony between the homophile community and the general public, to better the common welfare and secure the blessing of ...
Circle of Friends
core +1 more source
The use of lung ultrasound in the diagnosis of pneumothorax in trauma patients
Journal of Education, Health and Sport, 2020 Introduction and purpose: Pneumothorax is a condition in which air is present in the pleural cavity and often has a traumatic etiology. It can be a life-threatening condition, making quick and effective diagnosis essential.
Adrian Undziakiewicz +5 more
doaj +1 more source
Cancer Treatment and Research Communications, 2023 Introduction: Limited-stage small-cell lung cancer (LS-SCLC) is potentially curable with concurrent chemoradiation (CRT). Cisplatin is the preferred platinum for the chemotherapy backbone in national guidelines.
Shashank Sama +6 more
doaj +1 more source
Dense packings of congruent circles in a circle
Discrete Mathematics, 1998 Two methods based on the maximization of the minimum pairwise distance \(d\) among \(n\) points spread in a circle are proposed to generate packings of congruent circles in the circle. To overcome the difficulty caused by the nonsmoothness of that objective function, in the first method it is approximated by a smooth one, which can be regarded as a ...
Ronald L. Graham +3 more
openaire +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Postpartum depression in men – a common but rarely understood problem
Medycyna Ogólna i Nauki o Zdrowiu, 2021 Introduction Postpartum depression (PPPD) is defined as the occurrence of a depressive episode in the postpartum period, with a peak incidence between 3–6 months.
Magdalena Leśniewska +3 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source