Results 51 to 60 of about 129,001,126 (306)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Elemen-elemen Pembentuk Kota yang Berpengaruh terhadap Citra Kota (Studi Kasus: Kota Lama Semarang)

open access: yesJurnal Pembangunan Wilayah dan Kota, 2014
Kota Lama Semarang is an area where the Dutch colonial where there are buildings constructed since the Dutch era . The old city is often referred to as Little Netherland , with the city -like landscape in Europe and the canals that surround the Old City ...
Sintia Dewi Wulanningrum
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Assessing the Right to the City Theory from a Gender-Wise Perspective in order to Achieve Gender Inclusive Urban Space (Case Study: The City of Rasht) [PDF]

open access: yesزن در توسعه و سیاست
Justice is an inclusive and universal concept that has consistently been considered as a fundamental element of development. This concept may be interpreted differently from the standpoint of a variety of scientific and research fields.
Mehrnaz Molavi, Vahid Feizkhah
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Delaware City Public School

open access: yes, 2014
A reproduction of a photograph of the Delaware City Public ...
Nicholas, W.B.
core   +5 more sources

Study on the dynamic trends of moves into, out of, and within the city

open access: yesJapan Architectural Review, 2023
The purpose of this study was to compare the trends of moving in and out of the city and moving within the city, and to identify more detailed demographic and social dynamics within the city.
Yoko Shimizu   +3 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Psychological Security of Urban Dwellers and the Subject–Spatial Environment of the City

open access: yesUrban Science
The physical and spatial environment of a city is closely related to the general well-being of residents and their psychological security. The study aimed to examine the relationship between the physical and spatial urban environment and psychological ...
Olga Zotova, Lyudmila Tarasova
doaj   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

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