Results 61 to 70 of about 8,350,481 (309)

Elemen-elemen Pembentuk Kota yang Berpengaruh terhadap Citra Kota (Studi Kasus: Kota Lama Semarang)

Jurnal Pembangunan Wilayah dan Kota, 2014
Kota Lama Semarang is an area where the Dutch colonial where there are buildings constructed since the Dutch era . The old city is often referred to as Little Netherland , with the city -like landscape in Europe and the canals that surround the Old City ...
Sintia Dewi Wulanningrum
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Assessing the Right to the City Theory from a Gender-Wise Perspective in order to Achieve Gender Inclusive Urban Space (Case Study: The City of Rasht) [PDF]

زن در توسعه و سیاست
Justice is an inclusive and universal concept that has consistently been considered as a fundamental element of development. This concept may be interpreted differently from the standpoint of a variety of scientific and research fields.
Mehrnaz Molavi, Vahid Feizkhah
doaj   +1 more source

Understanding the City. Henri Lefebvre and Urban Studies [PDF]

, 2014
International audienceHenri Lefebvre is undoubtedly one of the most influential thinkers in the field of urban space and its organization; his theories offer reflections still valid for analyzing social relations in urban areas affected by the crisis of ...
Erdi Lelandais, Gülçin
core   +2 more sources

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Study on the dynamic trends of moves into, out of, and within the city

Japan Architectural Review, 2023
The purpose of this study was to compare the trends of moving in and out of the city and moving within the city, and to identify more detailed demographic and social dynamics within the city.
Yoko Shimizu, Toru Nakayama, Hiroko Shimizu, Hiroko Morita   +3 more
doaj   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Evaluation the Effects of Quality of Life on Citizen in Middle-Sized Cities (Case Study: The Cities of Borujerd and Kouhdasht, Lorestan) [PDF]

جغرافیا و آمایش شهری منطقه‌ای, 2016
Quality of urban life is one of the most important fields of urban studies in different countries that under the affection of factors such as time, place, personal and social values have a complex and multidimensional concept and often are measured by ...
Dr.Leila Soltani, Dr. Ahmad Khademalhoseini, Davar Amraee   +2 more
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source