Results 51 to 60 of about 324,727 (303)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Human rights abuses at a psychiatric hospital in KwaZulu-Natal
South African Journal of Psychiatry, 2007 Background:Following allegations of human rights abuses ata psychiatric hospital in Pietermaritzburg, KwaZulu-Natal, thatwere reported in one of the local newspapers, the nationaland provincial Ministers of Health visited the hospital.
D L Mkhize
doaj +1 more source
Non-discrimination under the European Convention on Human Rights: a critique of the UK Government's refusal to sign and ratify Protocol 12 [PDF]
, 2002 The European Convention on Human Rights does not contain a general prohibition of discrimination. Article 14 is accessory to the Convention’s other substantive guarantees and has no independent existence, with the result that certain forms of ...
Grief, Nicholas
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SpAds: political sherpas bridging minister and civil servant [PDF]
, 2020 This paper examines how opinion-shaping political and civil service stakeholders view the role and contribution of Special Political Advisers (SpAds) within the Westminster system of government. The literature only recently paid considered attention to
Kakabadse, Andrew P. +1 more
core +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
A Letter Invited on a Trip: Practice of Dealing with Complaints in Soviet Lithuania
Genocidas ir Rezistencija, 2007 In Soviet post-war society many letters / complaints which had little to do with ideology or police were written. People who wrote those complaints did not intend to report or punish anyone.
Dalia Marcinkevičienė
doaj +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
THE CONCEPT OF SOCIAL REINTEGRATION IN ROMANIA AFTER 1989 [PDF]
Challenges of the Knowledge Society, 2019 This paper attempts at pointing to the way in which social reintegration has evolved in Romania, starting with the communist era and ending with present time. First, we briefly outline the organisation of social reintegration under the communist regime
Constantin Marc NEAGU
doaj
Inclusive Study of Religions and World Views in Schools: Signposts from the Council of Europe
Social Inclusion, 2016 This article outlines some issues in incorporating the study of religions, together with non-religious world views, into the curricula of publicly funded schools in Western democratic states.
Robert Jackson
doaj +1 more source
Bargaining and Distribution of Power in the EU's Conciliation Committee [PDF]
The European Union (EU) has moved towards bicameralism, making the codecision procedure its most important mechanism for decision making. To gauge if European Parliament (EP) and Council of Ministers (CM) are equally powerful ‘codecision makers ...
Mika Widgrén, Stefan Napel
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