Results 41 to 50 of about 409,591 (393)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Three perspectives on the notion of ‘the best interests of the child’

open access: yesIn die Skriflig
The research reported in this article was centred on three research questions about the issue of ensuring that, in education and schooling, the principle of the best interests of the child is respected.
Johannes L. Van der Walt   +1 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Corporal Punishment in Light of the Criminal Policies of the Religious State [PDF]

open access: yesحقوق بشر, 2011
In the Islamic Republic of Iran in which a Muslim jurist has absolute authority over all its pillars and affairs, the supreme leader’s views play an important role both directly in determining the criminal policy for confronting and preventing behavioral
Mohammad Mahdi AnjomShoae
doaj  

Mandatory Relationships and Sex Education (RSE) in England—Educators’ Views on Children’s Rights

open access: yesYouth, 2023
Comprehensive sexuality education (known as Relationships and Sex Education (RSE) in England), which is age-appropriate, accurate, realistic and non-judgemental, is a tool that enables children and young people to make informed decisions about their ...
Aoife Caitriona Daly, Rachel Heah
doaj   +1 more source

Uzbekistan Supplementary NGO Report on the Implementation of the Convention on the Rights of the Child in the Republic of Uzbekistan [PDF]

open access: yes, 2001
[Excerpt] The Convention on the Rights of the Child (CRC) was one of the first international instruments to which the Republic of Uzbekistan acceded, and with parliamentary ratification on 9 December 1992, the Republic of Uzbekistan entered into a ...

core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Barnets rett til deltagelse i en barnevernkontekst

open access: yesNorsk Sosiologisk Tidsskrift, 2021
Artikkelen tematiserer og problematiserer hvordan barnets rett til å bli hørt kan ivaretas i en barnevernkontekst. Det argumenteres for at hensynet til det konkrete barnet krever et blikk ut over et rettslig perspektiv.
Hilde A. Aamodt
doaj   +1 more source

Implementing the UN Convention on the Rights of the Child [PDF]

open access: yesBMJ, 1996
In December 1991 the British government ratified the United Nations Convention on the Rights of the Child. The convention, adopted by the United Nations General Assembly in 1989, has now been ratified by an unprecedented 187 countries. It contains rights relating to every aspect of children's lives: rights to survival, development, protection, and ...
G, Lansdown, T, Waterston, D, Baum
openaire   +2 more sources

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