Results 21 to 30 of about 168,381 (293)
„PRACTICAL EXPERIENCE“ RELATED TO CRISIS COMMUNICATION DURING THE OIL AND OIL PRODUCTS SHORTAGE
Transactions of the VŠB: Technical University of Ostrava, Safety Engineering Series, 2018 Oil security (not just oil shortages, but many other possible scenarios) are challenges for society, businesses, or government authorities. The public sphere is in a difficult situation: positive and proactive communication can cause a panic reaction to ...
Lukáš HARAZIN +3 more
doaj +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
The Growth of Czech Feminism: Analyzing Resistance Activities through a Gendered Lens, 1968 to 1993 [PDF]
Gender a Výzkum, 2009 This paper explores how women’s roles and participation in resistance to Czechoslovak communism from 1968 to the Velvet Revolution serve as a base for Czech feminist thought.
Megan R. Martin
doaj
Matter and Radiation at Extremes, 2017 ELI-Beamlines (ELI-BL), one of the three pillars of the Extreme Light Infrastructure endeavour, will be in a unique position to perform research in high-energy-density-physics (HEDP), plasma physics and ultra-high intensity (UHI) (1022W/cm2) laser–plasma
S. Weber +39 more
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European Journal of Social Theory, 2005 This article discusses some aspects of developments in the Czech Republic during the 15 years since the downfall of the Communist regime. At the level of social structures, the dominant trend has been a rapid growth of inequality, which has blocked the development of a middle-class society.
openaire +3 more sources
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Influence of road salting on the adjacent Norway spruce (Picea abies) forest
Plant, Soil and Environment, 2011 Winter deicing and traffic spreads salt to road-adjacent Norway spruce trees in the form of spraying and salt slops. Our use of Na36Cl revealed roots as the main pathway of salt uptake.
S.T. Forczek +4 more
doaj +1 more source
Applied and Computational Mechanics, 2023 The onset and spread of flutter in a turbine blade cascade are numerically studied. Due to the application of the reduced-cascade model consisting of simple elements (springs, rigid bodies, linear dampers) and aeroelastic forces introduced by the ...
Pešek L. +3 more
doaj +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source