Results 31 to 40 of about 742,942 (286)

The Czech Republic

open access: yesEuropean Journal of Social Theory, 2005
This article discusses some aspects of developments in the Czech Republic during the 15 years since the downfall of the Communist regime. At the level of social structures, the dominant trend has been a rapid growth of inequality, which has blocked the development of a middle-class society.
openaire   +3 more sources

Guideline for handling pesticide residues in Czech organic production [PDF]

open access: yes, 2013
This document was prepared in the project «Development of guidelines for the use of pesticide analysis in organic inspection in the Czech Republic (sampling, evaluation and interpretation)». At the beginning of this project, a workshop with stakeholders
Bickel, Regula   +3 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Effect of feed supplements on the occurrence of coccidia oocysts in the digestive tract of pheasants

open access: yesActa Fytotechnica et Zootechnica, 2016
The occurrence of coccidiosis is an enormous problem of pheasant farming. The aim of this study is to show, that this disease can be cured by unconventional dietary supplements.
Luboš Zábranský   +6 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Torsion dissipated energy of hard rubbers as function of hyperelastic deformation energy of the Yeoh model

open access: yesApplied and Computational Mechanics, 2018
In this paper, we are proposing a new formulation of dissipated energy of hard rubbers as a function of the deformation energy expressed by the Yeoh hyperelastic model.
Šulc P.   +4 more
doaj   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

The helical domain of the EcoR124I motor subunit participates in ATPase activity and dsDNA translocation [PDF]

open access: yesPeerJ, 2017
Type I restriction-modification enzymes are multisubunit, multifunctional molecular machines that recognize specific DNA target sequences, and their multisubunit organization underlies their multifunctionality.
Vitali Bialevich   +8 more
doaj   +2 more sources

The conditions for implementing a circular economy in the Czech Republic [PDF]

open access: yes, 2019
In July 2018, measures of the European Commission regarding the Circular Economy Package (CEP) came into force. All EU Member States have two years since to implement these measures into their national legislations.
Bařinka, Karel   +8 more
core  

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold   +12 more
wiley   +1 more source

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