Results 111 to 120 of about 9,213,396 (310)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Digital health equity for older populations

open access: yesThe Lancet: Digital Health, 2023
The Lancet Digital Health
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Pregnancy in a pandemic: inequalities in maternal health

open access: yesThe Lancet: Digital Health, 2022
The Lancet Digital Health
doaj   +1 more source

Spatial Differentiation of Warming Effects in Urban Functional Areas Based on Warming Sensitivity Indices

open access: yesRedai dili
The POI data and Place2vec model within the third ring of Fuzhou City were used to identify the functional zones in the city, on the basis of which we were able to analyze the characteristics of the spatial differentiation of the thermal field levels in ...
Yang Hui   +4 more
doaj   +1 more source

Education Reform for the Digital Era [PDF]

open access: yes, 2012
Will the digital-learning movement repeat the mistakes of the charter-school movement? How much more successful might today's charter universe look if yesterday's proponents had focused on the policies and practices needed to ensure its quality, freedom,
Bryan C. Hassel   +7 more
core  

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Empowering women in health technology

open access: yesThe Lancet: Digital Health, 2022
The Lancet Digital Health
doaj   +1 more source

Unobtrusive measurement of cognitive load and physiological signals in uncontrolled environments

open access: yesScientific Data
While individuals fail to assess their mental health subjectively in their day-to-day activities, the recent development of consumer-grade wearable devices has enormous potential to monitor daily workload objectively by acquiring physiological signals ...
Christoph Anders   +3 more
doaj   +1 more source

Understanding the Challenges of the Digital Economy: The Nature of Digital Goods [PDF]

open access: yes
This article investigates the economic nature and characteristics of digital goods. Such goods are, due to their replicability, shown to be public goods (albeit in an evolutionary way) and durable goods.
Thierry RAYNA
core  

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