Results 121 to 130 of about 18,256,021 (363)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

The Stanford Digital Library Project

open access: yes, 1995
The Stanford Integrated Digital Library Project will develop enabling technologies for an integrated “virtual” library to provide an array of new services and uniform access to networked information collections. The Integrated Digital Library will create
CORPORATE The Stanford Digital Libraries Group
core   +1 more source

Close encounters of the digital kind: A research agenda for the digitalization of public services

open access: yesGovernment Information Quarterly, 2019
This paper contributes to e-government research by presenting a review and discussion on how digitalization of public services has affected the interaction between citizens and government.
Ida Lindgren   +3 more
semanticscholar   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Digital Accessibility as a Business Practice [PDF]

open access: yes, 2018
1. Getting Started2. Understanding the Big Picture3. The Committee and the Champion4. Creating Digital Accessibility Culture5. Procurement and Accessibility Policy6.
Digital Education Strategies - The Chang School
core  

It's not easy being green

open access: yesThe Lancet: Digital Health, 2021
The Lancet Digital Health
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

The Significance of Storage in the "Cost of Risk" of Digital Preservation

open access: yes, 2008
As storage costs drop, storage is becoming the lowest cost in a digital repository – and the biggest risk. We examine current modelling of costs and risks in digital preservation, concentrating on the Total Cost of Risk when using digital storage systems
Addis, Matthew   +5 more
core   +2 more sources

All things being equal: diversity in STEM

open access: yesThe Lancet: Digital Health, 2020
The Lancet Digital Health
doaj   +1 more source

Big data, artificial intelligence, and the opioid crisis

open access: yesThe Lancet: Digital Health, 2021
The Lancet Digital Health
doaj   +1 more source

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