Results 161 to 170 of about 276,427 (262)

The association of childhood HDL cholesterol with atherosclerotic cardiovascular disease events in adults: findings from the International Childhood Cardiovascular Cohort Consortium. [PDF]

Eur J Prev Cardiol
Wang J, Kartiosuo N, Raitakari OT, Viikari J, Juonala M, Bazzano LA, Sinaiko AR, Steinberger J, Daniels SR, Venn AJ, Magnussen C, Woo JG, Ramakrishnan R, Urbina EM, Kähönen M, Jacobs DR, Dwyer T.   +16 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Examining the heritability of actigraphy-assessed and parent-reported sleep duration in a community sample of twins across childhood and adolescence. [PDF]

Sleep Med
Bui C, Lemery-Chalfant K, Clifford S, Davis MC, Doane LD.   +4 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Lived Experiences and Long-Term Reflections on Early Marriage Among Palestinian Women: A Qualitative Study in the West Bank. [PDF]

Public Health Chall
Alqaissi N, Qtait M.
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Neurobiology of language in autism: a systematic review of pediatric studies. [PDF]

Brain Imaging Behav
Witt KM, Carnett A.
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Double burden of malnutrition by mid-childhood in an Indian birth cohort: a longitudinal study (2010-2021). [PDF]

Lancet Reg Health Southeast Asia
Yilmaz B, Mohan VR, John S, Kang G, Jebasingh F, Thomas N, Sonawane M, Kolthur-Seetharam U, Koshy B.   +8 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source