Results 31 to 40 of about 50,469 (311)

Influence of Hardened Surface on Low Cycle Fatigue Characteristics at Tension-compression and Bending

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2015
This paper analyses electromechanical hardening of the steel parts surface, when in the contact area so called “white layer” is formed. The experiments were performed to show the influence of “white layer” on strength of the steel C45 specimens under low
Artüras Sabaliauskas   +2 more
doaj   +1 more source

Contemporary patterns of transatlantic trade cooperation in a post-Brexit European Union (dis)order [PDF]

open access: yesCES Working Papers, 2020
This paper aims to examine the debate surrounding negotiations of the Transatlantic Trade and Investment Partnership (TTIP). The EU and US began negotiations for this comprehensive commercial agreement in July 2013 and have still not reached consensus ...
Iulia-Anamaria GHIDIU
doaj   +2 more sources

European Ai-Policy Space

open access: yesЕвразийская интеграция: экономика, право, политика, 2021
Artificial Intelligence (AI) is one of the central technologies of the fourth industrial revolution. A significant part of the production of surplus value in the XXI century is associated with the mastery and widespread introduction of technologies ...
R. S. Vykhodets
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Impact of European Union programs on the activities of the Third Polish Republic’s Parliament in the field of sport in the years 2004-2007

open access: yesCentral European Journal of Sport Sciences and Medicine, 2021
The aim of this paper is to show the impact of European Union programs on the activities of the Third Polish Republic’s Parliament in the field of sport in the years 2004-2007. The Republic of Poland joined the European Union (EU) on 1 May 2004.
Leonard Nowak, Maria Alicja Nowak
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

EERA White Paper A Just Energy Transition in the EU

open access: yes, 2023
Energy system transitions are complex socio-technical processes involving changes not only to energy technologies but alsoto the broader social and economic aspects of energy production and consumption. These energy transitions couldnegatively affect the people that they claim to serve, exacerbating current vulnerabilities and creating new ones ...
openaire   +3 more sources

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