Results 101 to 110 of about 21,707 (289)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

TRUST AND LEADERSHIP IN VIRTUAL TEAMS - The Perspective of Global Managers [PDF]

open access: yes, 2019
Purpose: The purpose of this thesis is to contribute to research on trust in virtual organizations and teams by letting managers of virtual teams elaborate on the concept of trust and leadership in virtual teams.
Ansari, Emil
core  

Impact of Training on Expectation of Employee and Employer: A comparative study

open access: yes, 2013
Organizations today spend millions of dollars on training to enhance the performance of their employees, which leads to formation of expectation on employers end as well as employees ends observing this phenomena ,this research was conducted to analyze ...
., Saqib Muneer   +2 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Managing Expectations [PDF]

open access: yesJournal of the National Comprehensive Cancer Network, 2019
openaire   +2 more sources

The Impact of Visualization and Expectation on Tourists’ Emotion and Satisfaction at the Destination

open access: yes, 2012
As tourist satisfaction is a clear goal in the tourism industry it is important to examine the consumers’ psychological process during the pre or post consumption experience including visualization, expectation, emotion and satisfaction of the ...
Lee, Woojin, Pachmayer, Ara
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

PEMETAAN PREFERENSI KONSUMEN SUPERMARKET DENGAN METODE KANO BERDASARKAN DIMENSI SERVQUAL

open access: yesJurnal Teknik Industri, 2004
The management of supermarket usually has some assumptions about the customers' expectation. Sometimes these assumtions do not reflect the nature of customers' expectations.
Kriswanto Widiawan, Irianty Irianty
doaj  

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