A Modular and Programmable Cas13d Platform for RNA Single Nucleotide Variant Detection
A scenario‐guided Cas13d platform enables configurable single nucleotide variant ribonucleic acid diagnostics through rule‐based guide design and ribonucleic acid binding domain engineering, supporting amplification‐free ultrasensitive detection and amplification‐coupled robust detection for accurate mutation classification in clinical tumor specimens.
Zeyu Wang +8 more
wiley +1 more source
This study assesses the impact of external shocks and exchange rate movements on prices. The main benefit of this granular analysis is its ability to capture heterogeneous impacts across different products and geographical areas, which is often ...
Syed Kalim Hyder Bukhari, Umar Mashhood
doaj
Climate change and environmental degradation: Evidence from SADC countries. [PDF]
Adediran OA +6 more
europepmc +1 more source
The optimal rate of inflation and the inflation target: international experience and the Hungarian perspective [PDF]
This article discusses the main factors considered in defining the country’s inflation target which was revised this year. Three key issues are covered: the theoretical and empirical literature dealing with the optimal level of inflation, international ...
Réka Juhász
core
Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES
In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu +5 more
wiley +1 more source
Analyzing the Effectiveness of Macroeconomic Policies in Addressing Poverty in Iraq: An Econometric Study considering Digital Transformation and Artificial Intelligence for the Period (2004-2024). [PDF]
Abdullah Abid Al Mihimdy N +2 more
europepmc +1 more source
This work introduces a theragenerative 3D‐printed biodegradable stent with Janus nanoarchitecture for spatially controlled vascular healing. A luminal tantalum ion–implanted surface accelerates endothelialization and hemocompatibility, while an abluminal sirolimus/poly‐L‐lactic acid–tantalum layer provides sustained drug release and suppresses smooth ...
Jong Hwa Seo +19 more
wiley +1 more source
The role of economic stability in boosting exports in COMESA: Threshold effects analysis. [PDF]
Addis AK, Xindong Y, Tianze M, Addis HK.
europepmc +1 more source
Inflation Dynamics in Romania – a New Keynesian Perspective [PDF]
We investigate in this paper the main factors which drive inflation in Romania: inflation persistence, inflation expectations and real economy variables.
Bogdan MURARASU, Nicoleta CIURILA
core
Stable Diffusion Models Reveal a Persisting Human–AI Gap in Visual Creativity
This study examines visual creativity in humans and generative AI using the TCIA framework. Human artists outperform AI overall, yet structured human guidance substantially improves AI outputs and evaluations. Findings reveal that alignment with human creativity depends critically on contextual framing, highlighting both the promise and current ...
Silvia Rondini +8 more
wiley +1 more source

