Results 91 to 100 of about 13,568,970 (312)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

K48-linked KLF4 ubiquitination by E3 ligase Mule controls T-cell proliferation and cell cycle progression

open access: yesNature Communications, 2017
The E3 ligase Mule has been previously reported to be essential for B cell development and function by modulating p53 ubiquitination and degradation. Here Haoet al.
Zhenyue Hao   +20 more
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Aile içi iletişim

open access: yesAnkara Sağlık Bilimleri Dergisi, 2012
Bireylerin kendini ve çevresini anlayabilmesi için iletişime girmesi önemli ve gereklidir. Ailenin çocuğu veya ergeni etkin bir şekilde dinlemesi ve onlara karşı dürüst ve açık olması çocukların duygu ve düşüncelerini etkin bir şekilde ifade etmesinde ...
Sultan Şahin, Neriman Aral
doaj   +1 more source

Compositional characterisation of the Themis family

open access: yes, 2015
Context. It has recently been proposed that the surface composition of icy main-belt asteroids (B-,C-,Cb-,Cg-,P-,and D-types) may be consistent with that of chondritic porous interplanetary dust particles (CPIDPs). Aims.
Binzel, R. P.   +7 more
core   +3 more sources

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Evaluation of primary mental health care in North West province – a qualitative view

open access: yesSouth African Journal of Psychiatry, 2008
Background. Due to many complaints by health care workers and patients and a perceived poor standard of care, the mental health care services in the North West province were assessed using quantitative and qualitative methods.
Claire van Deventer   +5 more
doaj   +1 more source

Evidence for the Inhibition by Temozolomide, an Imidazotetrazine Family Alkylator, of Intermediate-Conductance Ca2+-Activated K+ Channels in Glioma Cells [PDF]

open access: gold, 2016
Poh-Shiow Yeh   +8 more
openalex   +1 more source

Understanding the reasons for refusal of polio vaccine by families in Quetta Block, Pakistan

open access: diamond, 2022
Muhammad Samsoor Zarak   +9 more
openalex   +1 more source

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