Results 41 to 50 of about 242 (211)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Where are the women candidates during elections? A Fiji media case study

open access: yesPacific Journalism Review, 2013
This article examines the visibility of female election candidates, and females in general, in The Fiji Times and Fiji Sun during the 2006 general election.
Shazia Usman
doaj   +1 more source

Real-time qPCR improves meningitis pathogen detection in invasive bacterial-vaccine preventable disease surveillance in Fiji [PDF]

open access: yesScientific Reports, 2016
AbstractAs part of the World Health Organization Invasive Bacterial-Vaccine Preventable Diseases (IB-VPD) surveillance in Suva, Fiji, cerebrospinal fluid (CSF) samples from suspected meningitis patients of all ages were examined by traditional methods (culture, Gram stain, and latex agglutination for bacterial antigen) and qPCR for Streptococcus ...
Dunne, EM   +16 more
openaire   +3 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Times of sand: Sedimentary history and archaeology at the Sigatoka Dunes, Fiji

open access: yesGeoarchaeology, 2006
The orthodox archaeological sequence at the Sigatoka Dunes site (VL 16/1) in Fiji proposes three phases of occupation spanning Fijian prehistory, each associated with a period of dune stability. It has been taken as the standard model of Fijian prehistory for more than 30 years.
Anderson, Atholl   +7 more
openaire   +2 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Classification and ecological relevance of soundscapes in urban informal settlements

open access: yesPeople and Nature, 2023
Sound exerts wide‐ranging influence on humans. The quality of that influence depends on the sound source and context in which it is perceived, but nature sounds are generally preferred by people and associated with health and well‐being benefits. In many
Genie M. Fleming   +7 more
doaj   +1 more source

A Time Bomb Lies Buried: Fiji’s Road to Independence, 1960-1970 [PDF]

open access: yes, 2008
A Time Bomb Lies Buried discusses the debates which took place in Suva and London as well as the politics and processes which led Fiji to independence in 1970 after 96 years of colonial rule. It provides an essential background to understanding the crises and convulsions which have haunted Fiji ever since in its search for a constitutional settlement ...
openaire   +4 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Myosoft: An automated muscle histology analysis tool using machine learning algorithm utilizing FIJI/ImageJ software.

open access: yesPLoS ONE, 2020
MethodsMuscle sections were stained for cell boundary (laminin) and myofiber type (myosin heavy chain isoforms). Myosoft, running in the open access software platform FIJI (ImageJ), was used to analyze myofiber size and type in transverse sections of ...
Lucas Encarnacion-Rivera   +3 more
doaj   +1 more source

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