Results 121 to 130 of about 2,311,096 (292)
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Material, Trace, Trauma: Notes on some Recent Acquisitions at the Canadian War Museum and the Legacy of the First World War [PDF]
, 2017 Recent acquisitions at the Canadian War Museum are considered in relation to the radical innovations of soldier-artists who endured the somatic conditions of the First World War trenches, privileging materiality and psychic reality over visual perception.
Conley, Christine
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
, 2017 The First World War has generally faded from American memory, and is generally considered to have not cost the United States much. Although the country did not experience the total destruction that Europe endured, even small towns such as Gettysburg paid
Tracey, Jonathan
core
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Between Mars and Eros: British Army's Fight Against Venereal Disease during the First World War. [PDF]
Uisahak, 2020 Kang C.
europepmc +1 more source
Canada and the Korean War: Fifty Years On [PDF]
, 2012 In September 1998, the Canadian War Museum initiated a visiting speaker series to make available to the general public the latest research, debate and opinion on Canadian and international military history.
Stairs, Denis
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The Royal City at War: The Military Mobilization of Guelph, Ontario during the First 18 Months of the Second World War [PDF]
, 2012 The story of a country at war can be told at various levels. Traditional histories speak of generals and statesmen, of decisions made in cabinet rooms, war rooms, and dimly-lit clubs. Others choose to concentrate upon particular instances or groups, such
Braida, Jason R.H.
core +1 more source