Results 131 to 140 of about 461,298 (339)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
The Time of Tragedy: Thinking the Contemporary with Cavell and Agamben
Allow me to begin this article by asking the reader to visualize a brief yet disturbing scene. Assuming that you are sitting down whilst reading this, I ask you to imagine, if you will, that about a dozen paces from your seat, you see a young couple – an
Rudrum, David
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Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
L’utopia dell’aldilà in Luciano di Samosata
Annali Online dell'Università di Ferrara. Sezione Lettere, 2016 The aim of this essay is to analyse and describe the characteristics of the Hereafter in Lucian as a paradoxical utopia with a cynical origin. Specifically, in Hades we can find the egalitarian rules of democracy as would be conceivable on Earth.
Alberto Camerotto
doaj +1 more source
, 2014 Christian George approaches Charles Spurgeon’s sermons in terms of a preached Christology, that is, a Christology not confined to dogmatics but operative in preaching.
George, Christian
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Resurrection and the hereafter : A decisive proof of their reality
This book with its exquisite logic, not only proves decisively the existence of life after death, but it also makes clear the relevance of our states in the hereafter.
Said, Bediuzzaman Nursi
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Beli̇ef i̇n the hereafter percepti̇ons of mi̇ddle school students (Karaman sample)
, 2015 Yüksek Lisans Tezi. YÖK Tez Merkezi No: 407582Bu araştırmanın amacı, ortaokul düzeyinde eğitim-öğretim gören öğrencilerin âhiret inancı algılarını araştırmak, Din Kültürü ve Ahlak Bilgisi Dersi müfredatında belirlenen ahiret inancı ile ilgili amaç ve ...
Geçit, Halil
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