Results 91 to 100 of about 199,138 (264)

THE BASIC LINES OF COOPERATION BETWEEN THE DEPARTMENT OF PHILOLOGY AND HISTORY AT ANZHERO-SUDZHENSK BRANCH OF KEMEROVO STATE UNIVERSITY AND GENERAL EDUCATION INSTITUTIONS OF ANZHERO-SUDZHENSK AND THE NORTH OF KUZBASS

Вестник Кемеровского государственного университета, 2013
The paper addresses the basic lines of cooperation between the Department of Philology and History at AnzheroSudzhensk branch of Kemerovo State University and general education institutions in Anzhero-Sudzhensk and the North of Kuzbass.
E. N. Lisitskaya, T. L. Volchkova
doaj  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Reflexões sobre impostos e Raison d’État

Revista de Economia Mackenzie, 2004
The aim of the article is some common presuppositions, in modern history, of the ecclesiastical institutions as well as the State as the basis for the contro l and extraction of economic re s o u rces through the knowledge, the most accurate possible,
Roberto Romano
doaj  

Teacher Training at Classical Universities in Russia: Historical Context and Current Trends

Вестник Московского Университета. Серия 20: Педагогическое образование
Background. The relevance of this study is explained by the fact that Russian system of higher teacher education is experiencing a historical turning point.
Aydar M. Kalimullin, Roza A. Valeeva, Tatiana A. Baklashova   +2 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

The history of keratoprosthetics in the S. Fyodorov Eye Microsurgery Federal State Institution

Офтальмохирургия, 2013
ABSTRACT The article highlights a 45-year experience in keratoprosthetics at the S. Fyodorov Eye Microsurgery Federal State Institution. During this period, more than 1,000 keratoprostheses of different types has been implanted. The design features, advantages and disadvantages of foreign keratoprosthesis – Choyce-1, Choyce-2, H.
Z. I. Moroz, V. A. Vlasova, E. V. Kovshun   +2 more
openaire   +2 more sources

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Politics of Enforcing A “Multi-Ethnic” Society in Kosovo-A Brief History of Constitutional Development and State Building in Kosovo

Journal of Danubian Studies and Research, 2018
Constitutional law and state building in Kosovo was conducted with the goal of creating a multi-ethnic society; this impacted on the nature of the international administration from 1999-2008 and also the nature of Kosovo’s political/judicial structures
Xhafer Tahiri
doaj