Results 121 to 130 of about 1,972,647 (310)

Teacher Training at Classical Universities in Russia: Historical Context and Current Trends

Вестник Московского Университета. Серия 20: Педагогическое образование
Background. The relevance of this study is explained by the fact that Russian system of higher teacher education is experiencing a historical turning point.
Aydar M. Kalimullin, Roza A. Valeeva, Tatiana A. Baklashova   +2 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Institute of public environmental inspectors: the history of formation and the current state

Studia Humanitatis
The paper studies the problems and prospects of public environmental inspectors institute development in modern Russia. The author describes in detail the creation of this institution; the stages of its origin and formation are consistently considered.
openaire   +1 more source

Development strategies : integrating governance and growth [PDF]

A frontier challenge for development strategy is to move beyond prescribing optimal economic policies, and instead – taking a broad view of the interactions between economic, political and social constraints and dynamics -- to identify entry points ...
Fukuyama, Francis, Levy, Brian
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Politics of Enforcing A “Multi-Ethnic” Society in Kosovo-A Brief History of Constitutional Development and State Building in Kosovo

Journal of Danubian Studies and Research, 2018
Constitutional law and state building in Kosovo was conducted with the goal of creating a multi-ethnic society; this impacted on the nature of the international administration from 1999-2008 and also the nature of Kosovo’s political/judicial structures
Xhafer Tahiri
doaj  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

History of the State Water Resources Research Institute Program [PDF]

Open-File Report, 1984
openaire   +1 more source

Lawlessness and Economics: Alternative Modes of Governance [PDF]

How can property rights be protected and contracts be enforced in countries where the rule of law is ineffective or absent? How can firms from advanced market economies do business in such circumstances?
Avinash K. Dixit
core