Results 131 to 140 of about 1,972,647 (310)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Les collections de vêtements d’enfant, problèmes et perspectives

In Situ
Children's fashion remains a marginal museological subject in the contemporary museographic landscape and in particular in the institutions that should be in charge of this topic: fashion and local history museums.
Aude Le Guennec, Clare Rose
doaj   +1 more source

Centering Race and Ethnicity- Related Issues in Social Sciences Curricula [PDF]

, 2003
A 2002 review of the course requirements and electives of Economics, History, Political Science, and Sociology programs in thirty randomly selected state and private, doctoral-level and masters-level institutions produced 201 courses relating to the ...
Sheley, Joseph F.
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Aglomerações industriais no Estado de São Paulo

Economia Aplicada, 2001
This paper argues that, contrary to the trend in the Metropolitan Region ofthe State of São Paulo, the interior of the State is managing to increase its share of the country's manufacturing employment because of successful industrial clusters.
Wilson Suzigan, Joao Furtado, Renato Garcia, Sergio E. K. Sampaio   +3 more
doaj  

To the History of the Physical and Mathematical Research Institute of Saratov State University

Izvestiya of Saratov University. Physics
Background and Objectives: We provide information about the foundation of the Research Institute of Mathematics, Mechanics and Physics at Saratov State University in 1937, its structure, topics and first director Viktor V. Wagner. Materials and Methods: The organizational and vital details that accompanied the process of foundation and work of the ...
openaire   +2 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Book Review---Privatising Power Cuts? Ownership and Reform of State Electricity Boards in India [PDF]

This book discusses the functioning of the State Electricity Boards (commonly known as SEBs) of India and the implications of the new liberalized approach.
Deepak Kumar, P Nair
core