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A Novel Coupling Model of Physiological Degradation and Emotional State for Prediction of Alzheimer’s Disease Progression

open access: yesBrain Sciences, 2022
The prediction of Alzheimer’s disease (AD) progression plays a very important role in the early intervention of patients and the improvement of life quality. Cognitive scales are commonly used to assess the patient’s status.
Jiawei Yang   +2 more
doaj   +1 more source

Brain Entropy Mapping in Healthy Aging and Alzheimer’s Disease

open access: yesFrontiers in Aging Neuroscience, 2020
Alzheimer’s disease (AD) is a progressive neurodegenerative disease, for which aging remains the major risk factor. Aging is under a consistent pressure of increasing brain entropy (BEN) due to the progressive brain deteriorations.
Ze Wang   +1 more
doaj   +1 more source

Exploring protective and risk factors in the home environment in high-risk families – results from the Danish High Risk and Resilience Study—VIA 7

open access: yesBMC Psychiatry, 2022
Background Exposure to inadequate home environment may put the healthy development of familial high-risk children at risk. This study aimed to investigate associations between risk factors and an adequate home environment of children having a parent ...
Anne Amalie Elgaard Thorup   +15 more
doaj   +1 more source

Identification of Disease-Related Genes That Are Common between Alzheimer’s and Cardiovascular Disease Using Blood Genome-Wide Transcriptome Analysis

open access: yesBiomedicines, 2021
Accumulating evidence has suggested a shared pathophysiology between Alzheimer’s disease (AD) and cardiovascular disease (CVD). Based on genome-wide transcriptomes, specifically those of blood samples, we identify the shared disease-related signatures ...
Taesic Lee   +2 more
doaj   +1 more source

The MexBOL initiative [PDF]

open access: yesMitochondrial DNA, 2010
In 2005, Mexican researchers were invited to participate in the Barcode of Life Initiative. A few researchers showed interest in the initiative then, and in 2007, Paul Hebert from the University of Guelph in Canada came to Chetumal and Mexico City and presented his proposal to the scientific community of Mexico.
Patricia, Escalante   +2 more
openaire   +2 more sources

Reliable energy and responsive built environment: the missing links in COVID-19 response in resource-limited settings

open access: yesTropical Medicine and Health, 2020
Irrespective of how the COVID-19 pandemic evolves over time across the globe, our past experiences with comparable zoonotic diseases demonstrate the significance of having resilient primary healthcare systems to successfully respond to public health ...
Arvind Vashishta Rinkoo   +5 more
doaj   +1 more source

Confirmation of the presence of Anopheles stephensi among internally displaced people’s camps and host communities in Aden city, Yemen

open access: yesMalaria Journal, 2023
Background Declines in global malaria cases and deaths since the millennium are currently challenged by multiple factors including funding limitations, limits of, and resistance to vector control tools, and also recent spread of the invasive vector ...
Richard Allan   +5 more
doaj   +1 more source

Correlation between Alzheimer’s disease and type 2 diabetes using non-negative matrix factorization

open access: yesScientific Reports, 2021
Alzheimer’s disease (AD) is a complex and heterogeneous disease that can be affected by various genetic factors. Although the cause of AD is not yet known and there is no treatment to cure this disease, its progression can be delayed.
Yeonwoo Chung   +2 more
doaj   +1 more source

The TRANSPLANTEX initiative

open access: yesHuman Immunology, 2016
TRANSPLANTEX, a French "investment for the future" initiated consortium of leading transplant units and research laboratories across France and a number of European countries aims to unravel, through mainly high-throughput genomics (and other omics) analyses of donor and recipients, novel (a) non-HLA, histocompatibility antigens, whether inside, or ...
Bahram, Seiamak   +3 more
openaire   +3 more sources

Multi-PGS enhances polygenic prediction by combining 937 polygenic scores

open access: yesNature Communications, 2023
The predictive performance of polygenic scores (PGS) is largely dependent on the number of samples available to train the PGS. Increasing the sample size for a specific phenotype is expensive and takes time, but this sample size can be effectively ...
Clara Albiñana   +18 more
doaj   +1 more source

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