Results 91 to 100 of about 2,938,705 (290)
Ecological Solutions and EvidenceEcological restoration practitioners have debated the use of ecosystem models and reference ecosystems as targets for achieving ecological restoration of plant communities.
William Sluis +2 more
doaj +1 more source
International Journal of Biomedical Imaging, 2018 Early identification of dementia in the early or late stages of mild cognitive impairment (MCI) is crucial for a timely diagnosis and slowing down the progression of Alzheimer’s disease (AD).
Seyed Hossein Nozadi +2 more
doaj +1 more source
Evaluation of the Conrad N. Hilton Foundation Chronic Homelessness Initiative: 2015 [PDF]
, 2015 Under a September 2011 contract with the Conrad N. Hilton Foundation, Abt Associates has been conducting an evaluation of the Hilton Foundation's Chronic Homelessness Initiative, with the goal of answering the overarching question: Is the Chronic ...
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Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Eyes Wide Open: Deciding When to Launch a Community Initiative [PDF]
, 2003 Based on the experience and evaluation of Irvine's Community Foundations Initiative. Provides a guideline to use in the important due diligence that should come before giving any initiative the green ...
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Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Menthol cigarettes and the public health standard: a systematic review
BMC Public Health, 2017 Background Although menthol was not banned under the Tobacco Control Act, the law made it clear that this did not prevent the Food and Drug Administration from issuing a product standard to ban menthol to protect public health. The purpose of this review
Andrea C. Villanti +4 more
doaj +1 more source
The Syracuse Neighborhood Initiative Housing Market Study [PDF]
, 2000 The Syracuse Neighborhood Initiative is a collaborative effort between the City of Syracuse, local and national non-profit organizations, and private sector leaders.
Eileen Flanagan, Eric Hangen
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Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source