Results 101 to 110 of about 2,938,705 (290)

Fine resolution mapping of double-strand break sites for human ribosomal DNA units

open access: yesGenomics Data, 2016
DNA breakage arises during a variety of biological processes, including transcription, replication and genome rearrangements. In the context of disease, extensive fragmentation of DNA has been described in cancer cells and during early stages of ...
Bernard J. Pope   +3 more
doaj   +1 more source

The Food and Shelter Initiative: Preliminary Report [PDF]

open access: yes, 2001
Covers the first five months of the foundation's two-year initiative to address the needs of the homeless and hungry in the Greater Boston area.

core  

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Genetic interaction between TTG2 and AtPLC1 reveals a role for phosphoinositide signaling in a co-regulated suite of Arabidopsis epidermal pathways

open access: yesScientific Reports
The TTG2 transcription factor of Arabidopsis regulates a set of epidermal traits, including the differentiation of leaf trichomes, flavonoid pigment production in cells of the inner testa (or seed coat) layer and mucilage production in specialized cells ...
Aleah Goldberg   +9 more
doaj   +1 more source

Catalyzing Growth in the Women-Run Small and Medium Enterprises Sector (SMEs): Evaluating the Goldman Sachs 10,000 Women Initiative [PDF]

open access: yes, 2012
This document presents ICRWs initial (qualitative) evaluation of the Goldman Sachs "10,000 Women" initiative in India to identify early results of the program on women entrepreneurs' business skills, practices and growth. Launched in 2008, the initiative?

core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Detection of Alzheimer’s Disease Using Hybrid Meta-ROI of MRI Structural Images

open access: yesDiagnostics
Background: The averaged cortical thickness of meta-ROI is currently being used for the diagnosis and prognosis of Alzheimer’s disease (AD) using structural MRI brain images.
Xiaoming Zheng   +1 more
doaj   +1 more source

Author Correction: Composition and Use of Cannabis Extracts for Childhood Epilepsy in the Australian Community

open access: yesScientific Reports, 2018
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.
A. Suraev   +10 more
doaj   +1 more source

Preventing Gun Violence in Pediatrics [PDF]

open access: yes, 2018
Learn about the Violence Prevention Initiative at Children’s Hospital of Philadelphia, which has become a national and global model for hospital-based and communitydelivered violence prevention through educational programming in schools and the community,
Myers, PhD, Rachel
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

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