Results 21 to 30 of about 2,938,705 (290)

Identifying foetal forebrain interneurons as a target for monogenic autism risk factors and the polygenic 16p11.2 microdeletion

BMC Neuroscience, 2023
Background Autism spectrum condition or ‘autism’ is associated with numerous genetic risk factors including the polygenic 16p11.2 microdeletion. The balance between excitatory and inhibitory neurons in the cerebral cortex is hypothesised to be critical ...
Yifei Yang, Sam A. Booker, James M. Clegg, Idoia Quintana-Urzainqui, Anna Sumera, Zrinko Kozic, Owen Dando, Sandra Martin Lorenzo, Yann Herault, Peter C. Kind, David J. Price, Thomas Pratt   +11 more
doaj   +1 more source

Key factors to facilitate locally driven family planning programming: a qualitative analysis of urban stakeholder perspectives in Africa and Asia

Globalization and Health, 2021
Background There has been greater recognition of the importance of country ownership in global health and development. However, operationalising country ownership to ensure the scale up and sustainability of proven interventions remains elusive at best ...
Lisa Mwaikambo, Sarah Brittingham, Saori Ohkubo, Ruwaida Salem, Denis Joel Sama, Fatimata Sow, Deepti Mathur, Nneoma Nonyelum Anieto   +7 more
doaj   +1 more source

Treatment pattern trends of medications for type 2 diabetes in British Columbia, Canada

BMJ Open Diabetes Research & Care, 2022
Introduction Several new oral drug classes for type 2 diabetes (T2DM) have been introduced in the last 20 years accompanied by developments in clinical evidence and guidelines.
Ken Bassett, Colin R Dormuth, Wade Thompson, Greg Carney, Jason D Kim, Cait O'Sullivan, Josh Levin   +6 more
doaj   +1 more source

Intracortical diffusion tensor imaging signature of microstructural changes in frontotemporal lobar degeneration

Alzheimer’s Research & Therapy, 2021
Background Frontotemporal lobar degeneration (FTLD) is a neuropathological construct with multiple clinical presentations, including the behavioural variant of frontotemporal dementia (bvFTD), primary progressive aphasia—both non-fluent variant (nfvPPA ...
Mario Torso, Gerard R. Ridgway, Mark Jenkinson, Steven Chance, the Frontotemporal Lobar Degeneration Neuroimaging Initiative and the 4-Repeat Tau Neuroimaging Initiative (4RTNI)   +4 more
doaj   +1 more source

Moving from rabies research to rabies control: lessons from India [PDF]

, 2012
BACKGROUND: Despite the availability of effective interventions and public recognition of the severity of the problem, rabies continues to suffer neglect by programme planners in India and other low and middle income countries.
Abbas, Syed Shahid, Chauhan, Ritu Singh, Kakkar, Manish, Krishnan, Sampath, The Roadmap to Combat Zoonoses in India (RCZI) initiative,, Venkataramanan, Vidya   +5 more
core   +4 more sources

Quantitative genome-wide association analyses of receptive language in the Danish High Risk and Resilience Study

BMC Neuroscience, 2020
Background One of the most basic human traits is language. Linguistic ability, and disability, have been shown to have a strong genetic component in family and twin studies, but molecular genetic studies of language phenotypes are scarce, relative to ...
Ron Nudel, Camilla A. J. Christiani, Jessica Ohland, Md Jamal Uddin, Nicoline Hemager, Ditte Ellersgaard, Katrine S. Spang, Birgitte K. Burton, Aja N. Greve, Ditte L. Gantriis, Jonas Bybjerg-Grauholm, Jens Richardt M. Jepsen, Anne A. E. Thorup, Ole Mors, Thomas Werge, Merete Nordentoft   +15 more
doaj   +1 more source

Algorithmic surveillance of ICU patients with acute respiratory distress syndrome (ASIC): protocol for a multicentre stepped-wedge cluster randomised quality improvement strategy

BMJ Open, 2021
Introduction The acute respiratory distress syndrome (ARDS) is a highly relevant entity in critical care with mortality rates of 40%. Despite extensive scientific efforts, outcome-relevant therapeutic measures are still insufficiently practised at the ...
Stefan Kluge, Gernot Marx, Christian Putensen, Danny Ammon, Silke Haferkamp, Saskia Deffge, Thomas Wendt, Daniel Tiller, André Scherag, Philipp Simon, Johannes Bickenbach, Sebastian Johannes Fritsch, Julian Benedict Kunze, Oliver Maassen, Jennifer Kistermann, Irina Lutz, Nora Kristiana Voellm, Volker Lowitsch, Richard Polzin, Konstantin Sharafutdinov, Hannah Mayer, Lars Kuepfer, Rolf Burghaus, Walter Schmitt, Joerg Lippert, Morris Riedel, Chadi Barakat, André Stollenwerk, Simon Fonck, Sven Zenker, Felix Erdfelder, Daniel Grigutsch, Rainer Kram, Susanne Beyer, Knut Kampe, Jan Erik Gewehr, Friederike Salman, Patrick Juers, Emilia Wisotzki, Sebastian Gross, Lorenz Homeister, Frank Bloos, Susanne Mueller, Julia Palm, Nora Jahn, Markus Loeffler, Tobias Schuerholz, Petra Groeber, Andreas Schuppert   +48 more
doaj   +1 more source

Endourology, the initiative

Korean Journal of Urology, 2015
The development of minimally invasive surgical techniques in the field of urology is dynamic and has gained immense momentum recently. The endourology section of Korean Journal of Urology (KJU) has focused its efforts on introducing these novel methods and their clinical results to our readers as quickly as possible.
openaire   +2 more sources

Nigerian parents and caregivers knowledge, attitude and willingness to vaccinate their children against COVID-19

Frontiers in Public Health, 2023
ObjectivesIn order to achieve herd immunity against COVID-19, a significant proportion of the population will need to be vaccinated. Experts have recommended that African children be allowed to get vaccinated to protect them from emerging variants of ...
Azeezat Ajose, Azeezat Ajose, Cassandra Akinde, Cassandra Akinde, Azizat Ilo, Tobi Durojaiye, Tobi Durojaiye, Yusuf Shittu, Yusuf Shittu, Tolani Kadiri, Bisola Raheem, Bisola Raheem, Mujidat Kehinde Alamutu, Mujidat Kehinde Alamutu, Olamide Ojo, Alero Ann Roberts   +15 more
doaj   +1 more source

High-level artemisinin-resistance with quinine co-resistance emerges in P. falciparum malaria under in vivo artesunate pressure

BMC Medicine, 2018
Background Humanity has become largely dependent on artemisinin derivatives for both the treatment and control of malaria, with few alternatives available.
Rajeev K. Tyagi, Patrick J. Gleeson, Ludovic Arnold, Rachida Tahar, Eric Prieur, Laurent Decosterd, Jean-Louis Pérignon, Piero Olliaro, Pierre Druilhe   +8 more
doaj   +1 more source