Results 71 to 80 of about 2,938,705 (290)
The childhood development initiative: developing quality services [PDF]
, 2008 The Childhood Development Initiative (CDI) has created a ten-year strategy to improve the health, safety and learning of the children of Tallaght West, and to strengthen their sense of belonging in their own communities.
French, Geraldine, Zappone, Katherine
core +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Post‐initiation control by the initiation factor sigma [PDF]
Molecular Microbiology, 2008 SummaryBacterial core RNA polymerase can initiate transcription at promoters only if guided by a σ subunit that directs the core enzyme to a subset of σ‐specific promoters. Specific and stable interactions between the promoter DNA elements and σ are required for efficient promoter recognition.
openaire +2 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Evaluating Competing Agent Strategies for a Voice Email Agent
, 1997 This paper reports experimental results comparing a mixed-initiative to a system-initiative dialog strategy in the context of a personal voice email agent.
Di Fabbrizio, Giuseppe +4 more
core +4 more sources
Politics of Language: The California Bilingual Education Initiative [PDF]
, 1999 This essay examines issues of power and multiculturalism in relation to the education of children through debate over monolingual versus bilingual education and how language is a source of ...
Holstein, Amara
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Molecular AutismBackground Accurately determining the sample size (“N”) of a dataset is a key consideration for experimental design. Misidentification of sample size can lead to pseudoreplication, a process of artificially inflating the number of experimental replicates
Constantinos Eleftheriou +36 more
doaj +1 more source
The Beacon Community Centers Middle School Initiative: Final Report on Implementation and Youth Experience in the Initiative [PDF]
, 2011 The report evaluates New York City's Beacon Middle School Initiative, which was launched to increase services to middle-grades youth through programs in academics, life skills, career awareness, civic engagement, physical health, and arts and culture ...
Christina A. Russell +3 more
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FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source