Results 131 to 140 of about 134,904 (302)

Eomer Gets Poetic: Tolkien\u27s Alliterative Versecraft [PDF]

open access: yes, 2018
Throughout Tolkien\u27s professional career he dealt with a great number of texts that had varying views on the heroic, the romantic, the everyday world, and the role of Faerie.
Shelton, James
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Il tema della mostruosità in J.R.R. Tolkien

open access: yesStudi sulla Formazione
The literary Twentieth Century was marked by a global cultural phenomenon called Fantasy. The progenitor of this narrative vein was undoubtedly John Ronald Reuel Tolkien.
Ivano Sassanelli
doaj   +1 more source

Harry Potter, Frodo Baggings und der Kampf "gut gegen böse" [PDF]

open access: yes, 2009
Der Artikel geht dem Zusammenhang zwischen dem narrativen Sujet eines Kampfes "gut gegen böse" und seiner medialen Vermittlung am Beispiel der Verfilmungen von Harry Potter und dem Herrn der Ringe, aber auch mit einem Seitenblick zur ...
Jahraus, Oliver
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Tolkien and the Deadly Sin of Greed [PDF]

open access: yes, 2017
Tolkien’s genius as a writer and insight as a philosopher and theologian (of sorts) are reflected in his subtle yet impactful interweaving of the consequences of greed within the lives of the peoples of Middle-Earth.
Kieffer, Amanda A
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Intermedial Basis of Novels by J. Tolkien and Nick Perumov

open access: yesJournal of Danubian Studies and Research, 2018
The article deals with amodern understanding of the term intermedialism, characterize intermedial basis of the novel’s “The Lord of the Rings” by J. Tolkien and “The Ring of the Darkness” by Nick Perumov thanks to the spatial-visual literary-artistic ...
Оleg Manakhov
doaj  

J.R.R. Tolkien: the Forest and the City (2013), edited by Helen Conrad-O’Briain and Gerard Hynes. [PDF]

open access: yes, 2015
J.R.R. Tolkien: the Forest and the City (2013), edited by Helen Conrad-O’Briain and Gerard Hynes. Book Review by Kelley M.
Wickham-Crowley, Kelley M.
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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