Results 31 to 40 of about 5,136 (295)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
The Lord of the Rings” and the World Wars: The Applicability of Allegory [PDF]
, 2013 "Lord of the Rings" trilogy, written by John Ronal Reuel Tolkien between 1937 and 1949 is an epic novel, set in the fictional Middle Earth, in which a brotherhood of humans, elves and dwarves battles against a mighty force of evil, Sauron and his minions
Tandoğan, Sinan Haluk
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Education Sciences, 2021 Competence in “Cultural awareness and expressions” requires very stimulating activities for its development, and cinema can be used as an interesting enhancer of educational action.
Álvaro Pérez García +2 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Recovery, escape and consolation in the secondary worlds of The Lord of the Rings [PDF]
, 2008 Includes bibliographical references (leaves 96-100).J.R.R. Tolkien's essay "On Fairy-Stories" lays out three essential functions that all good fairy stories should fulfil: recovery, escape, and consolation.
Hazekamp, Robyn
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Framing audience prefigurations of The Hobbit: An Unexpected Journey: The roles of fandom, politics and idealised intertexts [PDF]
, 2014 Audiences for blockbuster event-film sequels and adaptations often formulate highly developed expectations, motivations, understandings and opinions well before the films are released.
Hight, Craig +3 more
core
Essays on the Lord of the Rings [PDF]
, 2017 Full collection of four essays on J.R.R. Tolkien's "The Lord of the Rings," comprising "Lord of the Rings: the anti-adventure," "Reader's Guide to the Fellowship of the Ring," "Reader's Guide to the Two Towers," and "The (True) Lord of the Ring ...
Patrick McEvoy-Halston
core +1 more source