Results 191 to 200 of about 185,736,576 (303)

Acinar‐Derived Organoids Reveal Stage‐Specific Control of Acinar Plasticity

Advanced Science, EarlyView.
An acinar‐derived organoid system maintains adult pancreatic acinar identity ex vivo, converts it along an ordered acinar‐to‐ductal‐like trajectory, and then partially restores it. Each transition carries its own signal requirement, with EGF/EGFR initiating conversion and a staged glucocorticoid–IGF1R switch driving redifferentiation.
Yongfei Hou, Siyu Li, Chunying Li, Zhifan Lin, Dan He, Li Yang, Liping Fu, Qianyue Zhang, Tianping Zhou, Yao Yao, Xiaolei Yin   +10 more
wiley   +1 more source

Hemostatic and Wound Healing Nonisocyanate Polyhydroxyurethanes (NIPHUs) Dressings from Soybean Oil: <i>In Vivo</i> Characterization. [PDF]

ACS Omega
Morales-Gonzalez MP, Valero MF, Díaz LE, Álvarez-Santos N, Espinosa-González AM, Benítez-Flores JDC, Avila-Acevedo JG, García-Bores AM.   +7 more
europepmc   +1 more source

Donor‐Cell Senescence Redirects PINK1‐Marked Mitochondrial Cargo From Mitophagy to Microvesicle Transfer Through SUMO3‐Stabilized HSPA9

Advanced Science, EarlyView.
ABSTRACT Extracellular vesicle therapies have been developed for tissue repair, but how donor‐cell senescence reshapes vesicle‐mediated mitochondrial transfer remains unclear. Here, we show that senescent adipose‐derived stem cells (ADSCs) redirect damaged mitochondria into microvesicles (MVs), converting protective vesicles into pro‐degenerative ...
Zixuan Ou, Mingke Zhao, Zhiwei Ling, Lianqi Peng, Bide Tong, Huaizhen Liang, Hongchuan Wang, Di Wu, Yifan Du, Zhi Du, Shihao Zhang, Yuyuan Jia, Yifan Qian, Gan Xu, Liuliang He, Gang Li, Shun Zhang, Lei Tan, Kun Wang, Xiaobo Feng, Cao Yang, Zhiwei Liao   +21 more
wiley   +1 more source

Ammonia Co-Firing in a Staged-Air Pulverized-Coal Boiler: Reactor-Network Prediction of Carbon Reduction and Nitrogen-Oxide Emissions. [PDF]

ACS Omega
Hu Z, Wang Q, Sun Z, Wang Y, Wu D, Wu S.
europepmc   +1 more source

Arhgef1 Deletion Disrupts Early Cortical Neurogenesis via PAK1 Overactivation and Causes Motor Dysfunction in Adulthood

Advanced Science, EarlyView.
ARHGEF1 plays a pivotal role in both embryonic cortical neurogenesis and adult motor function. During early development, it governs genesis of deep‐layer cortical neurons by negatively regulating RAC1/CDC42‐PAK1‐Cofilin signaling. In adulthood, ARHGEF1 is important for the maintenance of neuronal morphology and activity in the motor cortex, ensuring ...
Liuren Li, Xuanyue Ma, Zhenyu Ding, Bang Sun, Linglin Liu, Hei Matthew Yip, Wei Wang, Tianying Wu, Yuan Guo, Yinghui Peng, Shiqing Zhang, Jacque Pak Kan Ip, Li Zhang, Keshen Li, Lei Shi   +14 more
wiley   +1 more source

A Study on Pyrolysis Characteristics and Product Release Mechanisms of Oil Shale. [PDF]

ACS Omega
Li J, Yu X, Li Y, Li T, Yang M, Li X, Xie J, Li Y.   +7 more
europepmc   +1 more source

Plasma Membrane Lipid Asymmetry Dynamically Regulates Passive Diffusion

Advanced Science, EarlyView.
Passive diffusion enables hydrophobic molecules to cross the plasma membrane and exert their biological functions. This study demonstrates that plasma membrane lipid asymmetry, dynamically regulated by lipid scrambling, determines membrane permeability to lipophilic molecules and thereby modulates their cellular activities.
Jieming Ping, Wenliang Wang, Jinnuo Xu, Mengyun Yang, Ning Wu   +4 more
wiley   +1 more source

Machinability Enhancement of Ti6Al7Nb Biomedical Alloy Through MWCNT-Nanofluid MQL and Vortex Tube-Assisted Side Milling. [PDF]

Materials (Basel)
Khan AM, Gökduman B, Duman E, Hijji HH, Yapan YF, Khan MA, Javed A, Uysal A.   +7 more
europepmc   +1 more source

Interfacial and Hydration‐Associated Lithium Retention During FePO4 Regeneration from Spent LiFePO4 Cathodes

Advanced Science, EarlyView.
During iron phosphate regeneration, sequential washing distinguishes lithium fractions by accessibility: approximately 70% of precipitate‐associated lithium is washing‐removable, while approximately 30% remains after three cycles. Comparisons of simulated and practical systems associate retained lithium with hydrated amorphous Fe‐O‐P environments ...
Fei Han, Langyi Xiao, Genping Yi, Tian Liu, Shoudong Huang, Haonan Yan, Guang Yang, Liming Yang, Xubiao Luo   +8 more
wiley   +1 more source

CFD Simulation of Flow Behavior and Apparent Viscosity Distribution of Polymer Solution in a Rotating Packed Bed. [PDF]

Polymers (Basel)
Fu C, Wang ZY, Yin XS, Zhang YP, Zhu R, Zhang W, Huang B.   +6 more
europepmc   +1 more source