Results 151 to 160 of about 629,141 (310)

A Review of Interventions That Promote Meaning in Life

open access: yes, 2020
Increasing meaning in life in people undergoing various forms of trauma or adversity has shown promise as a means to improve well-being, coping mechanisms, and resilience.
Hamby, Sherry, Manco, Nicholas
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Base datos validación española Personal Meaning Profile-Brief

open access: yes, 2019
Dataset of the study on the Spanish validation of the Personal Meaning Profile-Brief (PMP-B)
Fernández Carreño, David
core  

Meaning of Life in Secondary Abstainers from Alcohol (Abstain From Alcohol and Meaning of Life)

open access: yes
Aim: Alcoholism is a major public health problem, and it has not yet been clarified which are the factors that influence the relapse of the disease. Aim of this research is to examine whether there is a connection between meaning of life in secondary ...
Degmečić, Dunja   +11 more
core   +1 more source

The process of families creating meaning of chronic illness and the medical community [PDF]

open access: yes, 2000
Plan BFamilies who have to cope with chronic illness or any other medical issue are often stressed beyond normal developmental stage compared to other families within that same developmental stage.
Routt, Katherine M.
core  

Alexithymia and Internet Addiction in Children: Meaning in Life as Mediator and Reciprocal Filial Piety as Moderator

open access: yes, 2023
Yuanyuan Li,1 Pengfei Yue,2,3 Min Zhang4 1College of Sports Medicine, Wuhan Sports University, Wuhan, Hubei, 430079, People’s Republic of China; 2Institute of Education Sciences, Hubei Normal University, Huangshi, Hubei, 435002, People’s Republic of ...
Li Y, Yue P, Zhang M
core  

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

Death and the Meaning of Life : A Critical Study of Metz’s Meaning in Life

open access: yes, 2015
In Meaning in Life: An Analytic Study, Thaddeus Metz advocates a kind of naturalistic objective theory of meaning in life, through a rejection of supernaturalism.
Yoshizawa, Fumitake
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

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