Results 51 to 60 of about 629,141 (310)

Pitfalls of anachronistic analysis: the book of Ecclesiastes, meaning of life and meaning in life

open access: yesSententiae, 2022
The article carries out a critical analysis of Arthur Kiefer's methodology (described in the “Ecclesiastes and the meaning of life in the ancient world”, Cambridge University Press, 2022), namely his concept of “meaning of life” applied to the analysis ...
Elvira Chukhrai
doaj   +1 more source

Action identification in chronic pain: how do people construct meaning in action? [PDF]

open access: yes, 2011
Background: Action Identification Theory holds that every action has different 'levels' of meaning. High levels confer greater meaning and are preferentially sought but when the action is interrupted lower level identities with reduced meaning are ...
Helen Louise Robinson, Robinson, Helen
core  

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

Miserable, Meaningless Lives, and Unwelcome Deaths

open access: yesProfil
David Benatar has been championing the cause of the overall badness of human lives since the turn of the century, most forcefully in his 2006 academic bestseller Better Never to Have Been. In his more recent book, The Human Predicament (OUP,
Friderik Klampfer
doaj   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker   +11 more
wiley   +1 more source

De-sportization of fighting contests: The Origins and Dynamics of No Holds Barred Events and the Theory of Sportization

open access: yes, 2006
On the basis of an empirical analysis of the emergence, spread and transformation of No Holds Barred fighting contests during the 1990s, we argue that Norbert Elias’s model of sportization represents a fruitful but not sufficiently differentiated ...
Bottenburg,van, Maarten   +5 more
core   +1 more source

Compositional evaluation of hot-pressed rapeseed cake for the purpose of bioplastic production [PDF]

open access: yes, 2021
Received: January 29th, 2021 ; Accepted: April 10th, 2021 ; Published: April 13th, 2021 ; Correspondence: katrin.jogi@student.emu.eeRapeseed is widely cultivated for biodiesel or food-grade oil production.
Jõgi, Katrin   +3 more
core   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási   +14 more
wiley   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

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